DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS

ABSTRACT. Myasthenia gravis is an autoimmune disease leading to weakness and pathological fatigue. The basis of the pathogenesis of myasthenia gravis is a disturbance of neurotransmission due to the influence of polyclonal autoantibodies on various structures of the neuromuscular junction. The recur...

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Main Authors: E. B. Vasilyeva, V. I. Kartavenko, S. S. Petrikov, S. A. Badygov, D. V. Sidnev, L. A. Savin
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2016-03-01
Series:Неотложная медицинская помощь
Subjects:
Online Access:https://www.jnmp.ru/jour/article/view/86
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author E. B. Vasilyeva
V. I. Kartavenko
S. S. Petrikov
S. A. Badygov
D. V. Sidnev
L. A. Savin
author_facet E. B. Vasilyeva
V. I. Kartavenko
S. S. Petrikov
S. A. Badygov
D. V. Sidnev
L. A. Savin
author_sort E. B. Vasilyeva
collection DOAJ
description ABSTRACT. Myasthenia gravis is an autoimmune disease leading to weakness and pathological fatigue. The basis of the pathogenesis of myasthenia gravis is a disturbance of neurotransmission due to the influence of polyclonal autoantibodies on various structures of the neuromuscular junction. The recurrent or progressive course is common for the disease. It is extremely difficult to suspect and diagnose this pathology for an anesthesiologist-resuscitator who doesn’t treat patients with myasthenia gravis in everyday practice, since the patients often arrive to mainstream hospitals in critical condition with incorrect diagnosis. only specialized units of neurology have electromyographs and equipment for particular immunological probes. We report a case of myasthenia gravis in a patient admitted to a hospital emergency room with the other disease suspected.
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spelling doaj.art-b0f2e4ef1b4841d9bfb11edd60c2a6042025-03-02T11:06:14ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172016-03-0103343784DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTSE. B. Vasilyeva0V. I. Kartavenko1S. S. Petrikov2S. A. Badygov3D. V. Sidnev4L. A. Savin5N.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineMoscow Myasthenia CenterA.I. Yevdokimov Moscow State University of Medicine and DentistryABSTRACT. Myasthenia gravis is an autoimmune disease leading to weakness and pathological fatigue. The basis of the pathogenesis of myasthenia gravis is a disturbance of neurotransmission due to the influence of polyclonal autoantibodies on various structures of the neuromuscular junction. The recurrent or progressive course is common for the disease. It is extremely difficult to suspect and diagnose this pathology for an anesthesiologist-resuscitator who doesn’t treat patients with myasthenia gravis in everyday practice, since the patients often arrive to mainstream hospitals in critical condition with incorrect diagnosis. only specialized units of neurology have electromyographs and equipment for particular immunological probes. We report a case of myasthenia gravis in a patient admitted to a hospital emergency room with the other disease suspected.https://www.jnmp.ru/jour/article/view/86paresis of the respiratory musclesbulbar syndromeneostigmine testelectromyography
spellingShingle E. B. Vasilyeva
V. I. Kartavenko
S. S. Petrikov
S. A. Badygov
D. V. Sidnev
L. A. Savin
DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS
Неотложная медицинская помощь
paresis of the respiratory muscles
bulbar syndrome
neostigmine test
electromyography
title DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS
title_full DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS
title_fullStr DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS
title_full_unstemmed DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS
title_short DIAGNOSIS AND TREATMENT OF NEW-ONSET MYASTHENIA GRAVIS IN CRITICALLY ILL PATIENTS
title_sort diagnosis and treatment of new onset myasthenia gravis in critically ill patients
topic paresis of the respiratory muscles
bulbar syndrome
neostigmine test
electromyography
url https://www.jnmp.ru/jour/article/view/86
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AT sspetrikov diagnosisandtreatmentofnewonsetmyastheniagravisincriticallyillpatients
AT sabadygov diagnosisandtreatmentofnewonsetmyastheniagravisincriticallyillpatients
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