Anti-EGFR V<sub>HH</sub> Antibody under Thermal Stress Is Better Solubilized with a Lysine than with an Arginine SEP Tag

Anti-EGFR V<sub>HH</sub> Antibody under Thermal Stress Is Better Solubilized with a Lysine than with an Arginine SEP Tag

In this study, we assessed the potential of arginine and lysine solubility-enhancing peptide (SEP) tags to control the solubility of a model protein, anti-EGFR V<sub>HH</sub>-7D12, in a thermally denatured state at a high temperature. We produced V<sub>HH</sub>-7D12 antibodie...

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Detaylı Bibliyografya
Asıl Yazarlar: Md. Golam Kibria, Akari Fukutani, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yutaka Kuroda
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2021-05-01
Seri Bilgileri:Biomolecules
Konular:
SEP tag
aggregation
single domain antibody
V<sub>HH</sub>
arginine SEP tag
lysine SEP tag
Online Erişim:https://www.mdpi.com/2218-273X/11/6/810

Internet

https://www.mdpi.com/2218-273X/11/6/810

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