Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial
Background and Objective: The prevention of clot formation during hemodialysis improves the effectiveness of treatment by maintaining patency in the dialyzer. This study was done to evaluate the effect of intermittent bolus of normal saline on the quality of clot formation in venous chamber and dial...
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2020-04-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/article-1-3699-en.html |
| _version_ | 1818255202748203008 |
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| author | Mitra Shirashiani Gholeamreza Roshandel Homeira Khoddam |
| author_facet | Mitra Shirashiani Gholeamreza Roshandel Homeira Khoddam |
| author_sort | Mitra Shirashiani |
| collection | DOAJ |
| description | Background and Objective: The prevention of clot formation during hemodialysis improves the effectiveness of treatment by maintaining patency in the dialyzer. This study was done to evaluate the effect of intermittent bolus of normal saline on the quality of clot formation in venous chamber and dialyzer.
Methods: In this clinical trial study, 51 eligible patients were divided into intervention (n=26) and control (n=25) groups. Patients in the control group received routine care and the intervention group received 100ml of normal saline, each hour, as an intermittent bolus, during 4 hours of dialysis beside the routine care. After three consecutive hemodialysis sessions (first round), all patients received routine care to clear the intervention effect (washout period). Then, patients crossed over from intervention group to control and vice versa. At the end of each session, the quality of clot formation in intravenous chamber and dialyzer was recorded and analyzed.
Results: The venous chamber of dialysis circuit in 74% of patient in intervention group no clot was formed, whereas in 58% of patient in control group it contained fibrous ring (P<0.05). After intervention, dialyzer of 68% of patients in intervention group, were free of clot, whereas in control group only 16% of dialyzers were free of clots (P<0.05).
Conclusion: Using intermittent bolus of normal saline during hemodialysis can reduce the risk of clot formation in venous chamber and dialyzer. |
| first_indexed | 2024-12-12T17:08:07Z |
| format | Article |
| id | doaj.art-b0f756fa1ab84063820955b96b10a3c7 |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-12-12T17:08:07Z |
| publishDate | 2020-04-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-b0f756fa1ab84063820955b96b10a3c72022-12-22T00:17:55ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802020-04-012212734Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trialMitra Shirashiani0Gholeamreza Roshandel1Homeira Khoddam2 M.Sc in Critical Care Nursing, School of Nursing and Midwifery, Golestan University of Medical Sciences, Gorgan, Iran. Epidemiologist, Associate Professor, Golestan Research Center of Gastroenterology and Hepatology (GRCGH), Gorgan, Iran. Ph.D in Nursing, Assistant Professor, Nursing Research Center, Golestan University of Medical Sciences, Gorgan, Iran Background and Objective: The prevention of clot formation during hemodialysis improves the effectiveness of treatment by maintaining patency in the dialyzer. This study was done to evaluate the effect of intermittent bolus of normal saline on the quality of clot formation in venous chamber and dialyzer. Methods: In this clinical trial study, 51 eligible patients were divided into intervention (n=26) and control (n=25) groups. Patients in the control group received routine care and the intervention group received 100ml of normal saline, each hour, as an intermittent bolus, during 4 hours of dialysis beside the routine care. After three consecutive hemodialysis sessions (first round), all patients received routine care to clear the intervention effect (washout period). Then, patients crossed over from intervention group to control and vice versa. At the end of each session, the quality of clot formation in intravenous chamber and dialyzer was recorded and analyzed. Results: The venous chamber of dialysis circuit in 74% of patient in intervention group no clot was formed, whereas in 58% of patient in control group it contained fibrous ring (P<0.05). After intervention, dialyzer of 68% of patients in intervention group, were free of clot, whereas in control group only 16% of dialyzers were free of clots (P<0.05). Conclusion: Using intermittent bolus of normal saline during hemodialysis can reduce the risk of clot formation in venous chamber and dialyzer.http://goums.ac.ir/journal/article-1-3699-en.htmlrenal dialysisblood coagulationsodium chloride |
| spellingShingle | Mitra Shirashiani Gholeamreza Roshandel Homeira Khoddam Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial مجله دانشگاه علوم پزشکی گرگان renal dialysis blood coagulation sodium chloride |
| title | Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial |
| title_full | Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial |
| title_fullStr | Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial |
| title_full_unstemmed | Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial |
| title_short | Effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit: A randomized clinical trial |
| title_sort | effect of intermittent normal saline bolus on the quality of clot formation in the dialyzer and the venous chamber of dialysis circuit a randomized clinical trial |
| topic | renal dialysis blood coagulation sodium chloride |
| url | http://goums.ac.ir/journal/article-1-3699-en.html |
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