Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention
Abstract Background Cardiac magnetic resonance (CMR) is an extremely accurate and useful modality that can give much data about myocardial damage after acute myocardial infarction and consequently can give a good idea about long-term prognosis. Unfortunately, this modality is still underused in Egyp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-12-01
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| Series: | The Egyptian Heart Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43044-019-0035-x |
| _version_ | 1818920929941520384 |
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| author | Diaa Kamal Ahmed S. Ibrahim Merhan Ahmed Nasr Sherihan S. Madkour |
| author_facet | Diaa Kamal Ahmed S. Ibrahim Merhan Ahmed Nasr Sherihan S. Madkour |
| author_sort | Diaa Kamal |
| collection | DOAJ |
| description | Abstract Background Cardiac magnetic resonance (CMR) is an extremely accurate and useful modality that can give much data about myocardial damage after acute myocardial infarction and consequently can give a good idea about long-term prognosis. Unfortunately, this modality is still underused in Egypt. We tried to assess the prognostic significance of different parameters derived from CMR in Egyptian patients presenting with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous intervention (PPCI). Twenty-five patients who presented with acute STEMI and were successfully reperfused by PPCI within 12 h from symptoms onset were included. CMR was performed 2–4 days after PPCI. Six months of long-term follow-up for major adverse cardiovascular events (re-infarction, new-onset heart failure and cardiac death) was done. CMR-derived parameters (edema volume, area at risk, infarction volume, infarction percentage, microvascular obstruction volume, microvascular obstruction percentage, myocardial salvage and myocardial salvage index) were analyzed in relation to incidence of major adverse cardiovascular events (MACE). Results Seven patients suffered from MACE. Univariate logistic regression analysis showed a significant correlation between edema volume (P = 0.04), area at risk (P = 0.05), infarction percentage (P = 0.05) and the occurrence of MACE. Multivariate logistic regression analysis showed that infarction percentage (P = 0.05) is the best parameter that can predict MACE. Conclusion Infarction percentage is potentially the most important prognosticator derived from CMR in Egyptian patients with acute STEMI successfully reperfused by PPCI. |
| first_indexed | 2024-12-20T01:29:34Z |
| format | Article |
| id | doaj.art-b0f8211f62424b459f6bc9fc7692f1df |
| institution | Directory Open Access Journal |
| issn | 2090-911X |
| language | English |
| last_indexed | 2024-12-20T01:29:34Z |
| publishDate | 2019-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Heart Journal |
| spelling | doaj.art-b0f8211f62424b459f6bc9fc7692f1df2022-12-21T19:58:08ZengSpringerOpenThe Egyptian Heart Journal2090-911X2019-12-017111710.1186/s43044-019-0035-xPrognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous interventionDiaa Kamal0Ahmed S. Ibrahim1Merhan Ahmed Nasr2Sherihan S. Madkour3Cardiology department, Faculty of medicine, Ain Shams UniversityRadiodiagnosis Department, Faculty of medicine, Ain Shams UniversityRadiodiagnosis Department, Faculty of medicine, Ain Shams UniversityRadiodiagnosis Department, Faculty of medicine, Ain Shams UniversityAbstract Background Cardiac magnetic resonance (CMR) is an extremely accurate and useful modality that can give much data about myocardial damage after acute myocardial infarction and consequently can give a good idea about long-term prognosis. Unfortunately, this modality is still underused in Egypt. We tried to assess the prognostic significance of different parameters derived from CMR in Egyptian patients presenting with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous intervention (PPCI). Twenty-five patients who presented with acute STEMI and were successfully reperfused by PPCI within 12 h from symptoms onset were included. CMR was performed 2–4 days after PPCI. Six months of long-term follow-up for major adverse cardiovascular events (re-infarction, new-onset heart failure and cardiac death) was done. CMR-derived parameters (edema volume, area at risk, infarction volume, infarction percentage, microvascular obstruction volume, microvascular obstruction percentage, myocardial salvage and myocardial salvage index) were analyzed in relation to incidence of major adverse cardiovascular events (MACE). Results Seven patients suffered from MACE. Univariate logistic regression analysis showed a significant correlation between edema volume (P = 0.04), area at risk (P = 0.05), infarction percentage (P = 0.05) and the occurrence of MACE. Multivariate logistic regression analysis showed that infarction percentage (P = 0.05) is the best parameter that can predict MACE. Conclusion Infarction percentage is potentially the most important prognosticator derived from CMR in Egyptian patients with acute STEMI successfully reperfused by PPCI.https://doi.org/10.1186/s43044-019-0035-xST-elevation myocardial infarctionPrimary percutaneous coronary interventionCardiac magnetic resonanceMajor adverse cardiovascular events |
| spellingShingle | Diaa Kamal Ahmed S. Ibrahim Merhan Ahmed Nasr Sherihan S. Madkour Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention The Egyptian Heart Journal ST-elevation myocardial infarction Primary percutaneous coronary intervention Cardiac magnetic resonance Major adverse cardiovascular events |
| title | Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention |
| title_full | Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention |
| title_fullStr | Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention |
| title_full_unstemmed | Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention |
| title_short | Prognostic value of different cardiac magnetic resonance imaging derived parameters in Egyptian patients with ST-elevation myocardial infarction after successful reperfusion by primary percutaneous intervention |
| title_sort | prognostic value of different cardiac magnetic resonance imaging derived parameters in egyptian patients with st elevation myocardial infarction after successful reperfusion by primary percutaneous intervention |
| topic | ST-elevation myocardial infarction Primary percutaneous coronary intervention Cardiac magnetic resonance Major adverse cardiovascular events |
| url | https://doi.org/10.1186/s43044-019-0035-x |
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