THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS
According to literature data, both the direct action of (B2 *, L, 2A) viral proteins and the inflammatory response of the body are distinguished among the Encephalomyocarditis virus (EMCV) virulence factors. Depending on the EMCV strain and the type of the infected animal, the severity and nature of...
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2019-07-01
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| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/1788 |
| _version_ | 1826568726291415040 |
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| author | Akop A. Kalajdzhjan Azamat Kh. Kade Pavel P. Polyakov Alla I. Gudmanova |
| author_facet | Akop A. Kalajdzhjan Azamat Kh. Kade Pavel P. Polyakov Alla I. Gudmanova |
| author_sort | Akop A. Kalajdzhjan |
| collection | DOAJ |
| description | According to literature data, both the direct action of (B2 *, L, 2A) viral proteins and the inflammatory response of the body are distinguished among the Encephalomyocarditis virus (EMCV) virulence factors. Depending on the EMCV strain and the type of the infected animal, the severity and nature of the disease is shown to be characterized by specific clinical manifestations. Differences in the pathogenetic mechanisms of tissue lesions depending on the magnitude of the virus infectious dose are established, e.g., in the development of EMCV-induced diabetes. The EMCV action was studied in vivo on such experimental animals as pigs, rodents and monkeys. The range of affected animals is extremely wide, with the infection being common almost everywhere. Thus, numerous works describe a fairly high immunological stratum among people, as well as disease outbreaks among the population. It is concluded that EMCV is dangerous not only for zoos and primatological centres, but also has a clear zoonotic potential. |
| first_indexed | 2024-03-07T21:47:46Z |
| format | Article |
| id | doaj.art-b0fb28e68c434430bdeb565a7a0a8695 |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2025-03-14T11:28:01Z |
| publishDate | 2019-07-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-b0fb28e68c434430bdeb565a7a0a86952025-03-02T10:05:34ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442019-07-0126311712810.25207/1608-6228-2019-26-3-117-1281116THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMSAkop A. Kalajdzhjan0Azamat Kh. Kade1Pavel P. Polyakov2Alla I. Gudmanova3Scientifc Research Institute of Medical PrimatologyKuban State Medical University, Ministry of Healthcare of the Russian FederationKuban State Medical University, Ministry of Healthcare of the Russian FederationKrasnodar City Clinical Hospital No. 3, Ministry of Healthcare of Krasnodar KraiAccording to literature data, both the direct action of (B2 *, L, 2A) viral proteins and the inflammatory response of the body are distinguished among the Encephalomyocarditis virus (EMCV) virulence factors. Depending on the EMCV strain and the type of the infected animal, the severity and nature of the disease is shown to be characterized by specific clinical manifestations. Differences in the pathogenetic mechanisms of tissue lesions depending on the magnitude of the virus infectious dose are established, e.g., in the development of EMCV-induced diabetes. The EMCV action was studied in vivo on such experimental animals as pigs, rodents and monkeys. The range of affected animals is extremely wide, with the infection being common almost everywhere. Thus, numerous works describe a fairly high immunological stratum among people, as well as disease outbreaks among the population. It is concluded that EMCV is dangerous not only for zoos and primatological centres, but also has a clear zoonotic potential.https://ksma.elpub.ru/jour/article/view/1788encephalomyocarditis virusemcv-induced diabetesemcv-induced myocarditisemcv virulence factors |
| spellingShingle | Akop A. Kalajdzhjan Azamat Kh. Kade Pavel P. Polyakov Alla I. Gudmanova THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS Кубанский научный медицинский вестник encephalomyocarditis virus emcv-induced diabetes emcv-induced myocarditis emcv virulence factors |
| title | THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS |
| title_full | THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS |
| title_fullStr | THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS |
| title_full_unstemmed | THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS |
| title_short | THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A LITERATURE REVIEW). PART II. PATHOGENESIS. THE CIRCLE OF SUSCEPTIBLE ORGANISMS |
| title_sort | encephalomyocarditis virus emcv and its zoonotic potential a literature review part ii pathogenesis the circle of susceptible organisms |
| topic | encephalomyocarditis virus emcv-induced diabetes emcv-induced myocarditis emcv virulence factors |
| url | https://ksma.elpub.ru/jour/article/view/1788 |
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