SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC

SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC

Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of hereditary and sporadic ccRCCs. CcRCC is associated with the reprogramming of fatty acid metabolism, and stearoyl-CoA des...

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Bibliographic Details
Main Authors: Athina Ganner, Antonia Philipp, Simon Lagies, Laura Wingendorf, Lu Wang, Felicitas Pilz, Thomas Welte, Kelli Grand, Soeren S. Lienkamp, Marinella Klein, Bernd Kammerer, Ian J. Frew, Gerd Walz, Elke Neumann-Haefelin
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
ccRCC
VHL
SCD5
fat-7
HIF
ceramide
Online Access:https://www.mdpi.com/2073-4409/12/6/835

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