Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data
<p>Abstract</p> <p>Background</p> <p>High incidence rates of gastrointestinal tract cancers have been reported in the Caspian region of Iran. This study aimed to: 1) describe the geographical spatial patterns of gastrointestinal tract cancer incidence based on cancer re...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2008-05-01
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| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/8/137 |
| _version_ | 1811279750846480384 |
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| author | Mohammad Kazem Nourijelyani Keramat Wolfe Rory Mahmoodi Mahmood Mohebbi Mohammadreza Zeraati Hojjat Fotouhi Akbar |
| author_facet | Mohammad Kazem Nourijelyani Keramat Wolfe Rory Mahmoodi Mahmood Mohebbi Mohammadreza Zeraati Hojjat Fotouhi Akbar |
| author_sort | Mohammad Kazem |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>High incidence rates of gastrointestinal tract cancers have been reported in the Caspian region of Iran. This study aimed to: 1) describe the geographical spatial patterns of gastrointestinal tract cancer incidence based on cancer registry data and, 2) determine whether geographical clusters of statistical significance exist.</p> <p>Methods</p> <p>The Babol Cancer Registry, which covers the two major northern Iranian provinces of Mazandaran and Golestan (total population = 4,484,622) was used to identify new gastrointestinal tract cancer cases during 2001 to 2005. Age-specific cancer incidence rates were calculated for 7 gastrointestinal tract cancer sites in 26 wards of the Mazandaran and Golestan provinces. Spatial autocorrelation indices, hierarchical Bayesian Poisson models, and spatial scan statistics were used in measuring the geographic pattern and clusters.</p> <p>Results</p> <p>There were non-random spatial patterns in esophageal and stomach cancers that were similar for both sexes. Clusters of high incidence were identified in esophageal, stomach, colorectal and liver cancer for both sexes, as well as a possible cluster of pancreas cancer in males.</p> <p>Conclusion</p> <p>Gastrointestinal tract cancers exhibit significant spatial clustering of risk in northern Iran. Further work is needed to relate these geographical patterns to information on potential life-style and environmental factors.</p> |
| first_indexed | 2024-04-13T01:01:21Z |
| format | Article |
| id | doaj.art-b0feecbcf4a84ea0aab15636a9460cf1 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-04-13T01:01:21Z |
| publishDate | 2008-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-b0feecbcf4a84ea0aab15636a9460cf12022-12-22T03:09:28ZengBMCBMC Cancer1471-24072008-05-018113710.1186/1471-2407-8-137Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry dataMohammad KazemNourijelyani KeramatWolfe RoryMahmoodi MahmoodMohebbi MohammadrezaZeraati HojjatFotouhi Akbar<p>Abstract</p> <p>Background</p> <p>High incidence rates of gastrointestinal tract cancers have been reported in the Caspian region of Iran. This study aimed to: 1) describe the geographical spatial patterns of gastrointestinal tract cancer incidence based on cancer registry data and, 2) determine whether geographical clusters of statistical significance exist.</p> <p>Methods</p> <p>The Babol Cancer Registry, which covers the two major northern Iranian provinces of Mazandaran and Golestan (total population = 4,484,622) was used to identify new gastrointestinal tract cancer cases during 2001 to 2005. Age-specific cancer incidence rates were calculated for 7 gastrointestinal tract cancer sites in 26 wards of the Mazandaran and Golestan provinces. Spatial autocorrelation indices, hierarchical Bayesian Poisson models, and spatial scan statistics were used in measuring the geographic pattern and clusters.</p> <p>Results</p> <p>There were non-random spatial patterns in esophageal and stomach cancers that were similar for both sexes. Clusters of high incidence were identified in esophageal, stomach, colorectal and liver cancer for both sexes, as well as a possible cluster of pancreas cancer in males.</p> <p>Conclusion</p> <p>Gastrointestinal tract cancers exhibit significant spatial clustering of risk in northern Iran. Further work is needed to relate these geographical patterns to information on potential life-style and environmental factors.</p>http://www.biomedcentral.com/1471-2407/8/137 |
| spellingShingle | Mohammad Kazem Nourijelyani Keramat Wolfe Rory Mahmoodi Mahmood Mohebbi Mohammadreza Zeraati Hojjat Fotouhi Akbar Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data BMC Cancer |
| title | Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data |
| title_full | Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data |
| title_fullStr | Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data |
| title_full_unstemmed | Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data |
| title_short | Geographical spread of gastrointestinal tract cancer incidence in the Caspian Sea region of Iran: Spatial analysis of cancer registry data |
| title_sort | geographical spread of gastrointestinal tract cancer incidence in the caspian sea region of iran spatial analysis of cancer registry data |
| url | http://www.biomedcentral.com/1471-2407/8/137 |
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