Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity

Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity

Abstract Excessive osteoclast activation, which depends on dramatic changes in actin dynamics, causes osteoporosis (OP). The molecular mechanism of osteoclast activation in OP related to type 1 diabetes (T1D) remains unclear. Glia maturation factor beta (GMFB) is considered a growth and differentiat...

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Bibliographic Details
Main Authors: Si Shi, Huijie Gu, Jinyuan Xu, Wan Sun, Caiyin Liu, Tong Zhu, Juan Wang, Furong Gao, Jieping Zhang, Qingjian Ou, Caixia Jin, Jingying Xu, Hao Chen, Jiao Li, Guotong Xu, Haibin Tian, Lixia Lu
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00980-8

Internet

https://doi.org/10.1038/s12276-023-00980-8

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