An unexpected strategy to alleviate hypoxia limitation of photodynamic therapy by biotinylation of photosensitizers

Type I photodynamic therapy (PDT) sensitizers show good hypoxia tolerance but only few strategies are available for the design of purely organic Type I photosensitizers (PS). Here, the authors use biotinylation as design strategy to obtain PS-Biotin sensitizers with high efficiency for the generatio...

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Bibliographic Details
Main Authors: Jing An, Shanliang Tang, Gaobo Hong, Wenlong Chen, Miaomiao Chen, Jitao Song, Zhiliang Li, Xiaojun Peng, Fengling Song, Wen-Heng Zheng
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29862-9

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