Epidemiology of diagnosed cluster headache in Norway
Background: Cluster headache (CH) is one of the most painful conditions in humans and there is limited epidemiological data on this debilitating condition. Objectives: To describe the epidemiology of CH in Norway Methods: We conducted a nationwide study to investigate the prevalence, incidence, and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-02-01
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| Series: | Cephalalgia Reports |
| Online Access: | https://doi.org/10.1177/25158163221075569 |
| _version_ | 1818896956984918016 |
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| author | Joan Crespi Sasha Gulati Øyvind Salvesen Daniel Fossum Bratbak David W Dodick Manjit Singh Matharu Erling Tronvik |
| author_facet | Joan Crespi Sasha Gulati Øyvind Salvesen Daniel Fossum Bratbak David W Dodick Manjit Singh Matharu Erling Tronvik |
| author_sort | Joan Crespi |
| collection | DOAJ |
| description | Background: Cluster headache (CH) is one of the most painful conditions in humans and there is limited epidemiological data on this debilitating condition. Objectives: To describe the epidemiology of CH in Norway Methods: We conducted a nationwide study to investigate the prevalence, incidence, and comorbidity of CH in Norway between January 1 2008 and December 31 2016. Treatment and outcome data from the Norwegian patient registry and the Norwegian prescription database were linked on an individual basis. Results: Among 3,892,260 individuals ≥18 years old of age, we identified a total of 1891 patients with CH. The prevalence of CH was 48.6 per 100,000, and the male-to-female ratio was 1.47. The estimated incidence of CH was 3.0 per 100,000/year. Among patients with CH, increased age and sex adjusted odds ratios ([OR], all with p -values <0.0001, were observed for medication-induced headache (OR 50.7, 95% CI 36.7–69.9), migraine (OR 25.2, 95% CI 22.5–28.3), chronic posttraumatic headache (OR 22.2, 95% CI 12.8–38.45), history of cranial trauma (OR 1.9, 95% CI 1.5–2.4), somatoform disorders (OR 4.2, 95% CI 3.0–5.8), suicide attempt (OR 3.9, 95% CI 2.6–5.8), personality disorder (OR 3.6, 95% CI 2.6–4.9), bipolar disorder (OR 3.6, 95% CI 2.8–4.8), peptic ulcer (OR 2.8, 95% CI 2.3–3.3), depression (OR 2.8, 95% CI 2.4–3.1), substance abuse (OR 2.6, 95% CI 2.0–3.3), and cerebrovascular disease (OR 2.4, 95% CI 1.8–3.1). Use of opioid analgesics during the study period was more common among patients with CH compared to others (81% vs. 22%, sex and age adjusted OR 23.4, 95% CI 20.8–26.2, p < 0.0001). |
| first_indexed | 2024-12-19T19:08:32Z |
| format | Article |
| id | doaj.art-b10d010af3e04f06baa530bed022c6e7 |
| institution | Directory Open Access Journal |
| issn | 2515-8163 |
| language | English |
| last_indexed | 2024-12-19T19:08:32Z |
| publishDate | 2022-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cephalalgia Reports |
| spelling | doaj.art-b10d010af3e04f06baa530bed022c6e72022-12-21T20:09:23ZengSAGE PublishingCephalalgia Reports2515-81632022-02-01510.1177/25158163221075569Epidemiology of diagnosed cluster headache in NorwayJoan Crespi0Sasha Gulati1Øyvind Salvesen2Daniel Fossum Bratbak3David W Dodick4Manjit Singh Matharu5Erling Tronvik6 Department of Neuromedicine and Movement Science, NTNU (Norwegian University of Science and Technology), Trondheim, Norway Department of Neurosurgery, St. Olav’s University Hospital, Trondheim, Norway Unit for Applied Clinical Research, Department of Cancer Research and Molecular Medicine, NTNU (Norwegian University of Science and Technology), Trondheim, Norway Department of Neurosurgery, St. Olav’s University Hospital, Trondheim, Norway Mayo Clinic, Phoenix, AZ, USA UCL Queen Square Institute of Neurology and The National Hospital of Neurology and Neurosurgery, London, UK Department of Neuromedicine and Movement Science, NTNU (Norwegian University of Science and Technology), Trondheim, NorwayBackground: Cluster headache (CH) is one of the most painful conditions in humans and there is limited epidemiological data on this debilitating condition. Objectives: To describe the epidemiology of CH in Norway Methods: We conducted a nationwide study to investigate the prevalence, incidence, and comorbidity of CH in Norway between January 1 2008 and December 31 2016. Treatment and outcome data from the Norwegian patient registry and the Norwegian prescription database were linked on an individual basis. Results: Among 3,892,260 individuals ≥18 years old of age, we identified a total of 1891 patients with CH. The prevalence of CH was 48.6 per 100,000, and the male-to-female ratio was 1.47. The estimated incidence of CH was 3.0 per 100,000/year. Among patients with CH, increased age and sex adjusted odds ratios ([OR], all with p -values <0.0001, were observed for medication-induced headache (OR 50.7, 95% CI 36.7–69.9), migraine (OR 25.2, 95% CI 22.5–28.3), chronic posttraumatic headache (OR 22.2, 95% CI 12.8–38.45), history of cranial trauma (OR 1.9, 95% CI 1.5–2.4), somatoform disorders (OR 4.2, 95% CI 3.0–5.8), suicide attempt (OR 3.9, 95% CI 2.6–5.8), personality disorder (OR 3.6, 95% CI 2.6–4.9), bipolar disorder (OR 3.6, 95% CI 2.8–4.8), peptic ulcer (OR 2.8, 95% CI 2.3–3.3), depression (OR 2.8, 95% CI 2.4–3.1), substance abuse (OR 2.6, 95% CI 2.0–3.3), and cerebrovascular disease (OR 2.4, 95% CI 1.8–3.1). Use of opioid analgesics during the study period was more common among patients with CH compared to others (81% vs. 22%, sex and age adjusted OR 23.4, 95% CI 20.8–26.2, p < 0.0001).https://doi.org/10.1177/25158163221075569 |
| spellingShingle | Joan Crespi Sasha Gulati Øyvind Salvesen Daniel Fossum Bratbak David W Dodick Manjit Singh Matharu Erling Tronvik Epidemiology of diagnosed cluster headache in Norway Cephalalgia Reports |
| title | Epidemiology of diagnosed cluster headache in Norway |
| title_full | Epidemiology of diagnosed cluster headache in Norway |
| title_fullStr | Epidemiology of diagnosed cluster headache in Norway |
| title_full_unstemmed | Epidemiology of diagnosed cluster headache in Norway |
| title_short | Epidemiology of diagnosed cluster headache in Norway |
| title_sort | epidemiology of diagnosed cluster headache in norway |
| url | https://doi.org/10.1177/25158163221075569 |
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