A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern
Acute generalized exanthematous pustulosis is a rare severe cutaneous adverse reaction that classically presents in intertriginous or flexural areas and subsequently spreads diffusely across the trunk and extremities. To date, few cases of acute generalized exanthematous pustulosis arising in a phot...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-02-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X241231526 |
| _version_ | 1797307159043637248 |
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| author | Charles D Lange Laura Madden Eva Rawlings Parker |
| author_facet | Charles D Lange Laura Madden Eva Rawlings Parker |
| author_sort | Charles D Lange |
| collection | DOAJ |
| description | Acute generalized exanthematous pustulosis is a rare severe cutaneous adverse reaction that classically presents in intertriginous or flexural areas and subsequently spreads diffusely across the trunk and extremities. To date, few cases of acute generalized exanthematous pustulosis arising in a photodistributed pattern are documented. Herein, we describe the second known case of photodistributed generalized exanthematous pustulosis arising in association with oral terbinafine use, providing a summary of the previously documented cases along with exploration of the potential pathophysiological mechanisms for this cutaneous reaction. |
| first_indexed | 2024-03-08T00:53:10Z |
| format | Article |
| id | doaj.art-b10e54d66f2e4870b2173297ff995ce4 |
| institution | Directory Open Access Journal |
| issn | 2050-313X |
| language | English |
| last_indexed | 2024-03-08T00:53:10Z |
| publishDate | 2024-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj.art-b10e54d66f2e4870b2173297ff995ce42024-02-14T19:03:24ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2024-02-011210.1177/2050313X241231526A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed patternCharles D Lange0Laura Madden1Eva Rawlings Parker2Indiana University School of Medicine, Indianapolis, IN, USADermatology Physicians of Connecticut, Branford, CT, USACenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN, USAAcute generalized exanthematous pustulosis is a rare severe cutaneous adverse reaction that classically presents in intertriginous or flexural areas and subsequently spreads diffusely across the trunk and extremities. To date, few cases of acute generalized exanthematous pustulosis arising in a photodistributed pattern are documented. Herein, we describe the second known case of photodistributed generalized exanthematous pustulosis arising in association with oral terbinafine use, providing a summary of the previously documented cases along with exploration of the potential pathophysiological mechanisms for this cutaneous reaction.https://doi.org/10.1177/2050313X241231526 |
| spellingShingle | Charles D Lange Laura Madden Eva Rawlings Parker A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern SAGE Open Medical Case Reports |
| title | A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern |
| title_full | A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern |
| title_fullStr | A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern |
| title_full_unstemmed | A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern |
| title_short | A case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern |
| title_sort | case report of terbinafine induced acute generalized exanthematous pustulosis in a striking photodistributed pattern |
| url | https://doi.org/10.1177/2050313X241231526 |
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