Second-Generation Polyamidoamine Dendrimer Conjugated with Oligopeptides Can Enhance Plasmid DNA Delivery In Vitro

Second-Generation Polyamidoamine Dendrimer Conjugated with Oligopeptides Can Enhance Plasmid DNA Delivery In Vitro

Poly(amidoamine) (PAMAM) dendrimers have attracted considerable attention in the field of gene therapy due to their flexibility in introducing different functional moieties and reduced toxicity at low generations. However, their transfection efficiency remains a limitation. Therefore, an essential a...

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Bibliographic Details
Main Authors: Seongyeon Kim, Le Thi Thuy, Jeil Lee, Joon Sig Choi
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
PAMAM
gene carrier
RRHRH
oligopeptide
transfection
Online Access:https://www.mdpi.com/1420-3049/28/22/7644

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