Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report
Inherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of a successful pregnancy outcome in a 37-year old woman with hypofibrinogenaemia. She was referred to a coagulation test in the first...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine
2020-01-01
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| Series: | Scripta Medica |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2020/2490-33292002124S.pdf |
| _version_ | 1818347685530304512 |
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| author | Simeonova-Krstevska Slagjana Todorovska Elizabeta Makarovska-Bojadjieva Tatjana Petković Elena Stojčevski Saso Samardžiski Igor Spasovski Saso Dejanova Violeta Grubović Radica Raka Florije Jovanovska Viktorija Todorovska Irena Livrinova Vesna Sima Aneta Jovčevski Sasa Milkovski Daniel |
| author_facet | Simeonova-Krstevska Slagjana Todorovska Elizabeta Makarovska-Bojadjieva Tatjana Petković Elena Stojčevski Saso Samardžiski Igor Spasovski Saso Dejanova Violeta Grubović Radica Raka Florije Jovanovska Viktorija Todorovska Irena Livrinova Vesna Sima Aneta Jovčevski Sasa Milkovski Daniel |
| author_sort | Simeonova-Krstevska Slagjana |
| collection | DOAJ |
| description | Inherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of a successful pregnancy outcome in a 37-year old woman with hypofibrinogenaemia. She was referred to a coagulation test in the first trimester because of history of preeclampsia and HELLP syndrome in previous pregnancy. Hypofibrinogenaemia was diagnosed with fibrinogen level of 0.7 g/L. During the pregnancy she was regularly monitored for fibrinogen levels and multiple cryoprecipitate concentrates were given. She delivered at 39th gestation week, with elective caesarean section under general anaesthesia. There was one episode of postpartum haemorrhage treated with 2 units of red blood cells, repeated infusions of cryoprecipitate to obtain the level of fibrinogen of 2 g/L. She was discharged on the 6th postpartum day in a good condition. In these disorders levels of fibrinogen should be higher than 1 g/L during pregnancy or 2 g/L in case of caesarean section for successful prenatal and peripartal management. |
| first_indexed | 2024-12-13T17:38:05Z |
| format | Article |
| id | doaj.art-b113f1fe897d4bf993a4e1a869522db0 |
| institution | Directory Open Access Journal |
| issn | 2490-3329 2303-7954 |
| language | English |
| last_indexed | 2024-12-13T17:38:05Z |
| publishDate | 2020-01-01 |
| publisher | Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine |
| record_format | Article |
| series | Scripta Medica |
| spelling | doaj.art-b113f1fe897d4bf993a4e1a869522db02022-12-21T23:36:52ZengMedical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of MedicineScripta Medica2490-33292303-79542020-01-015121241282490-33292002124SMultidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case reportSimeonova-Krstevska Slagjana0Todorovska Elizabeta1Makarovska-Bojadjieva Tatjana2Petković Elena3Stojčevski Saso4Samardžiski Igor5Spasovski Saso6Dejanova Violeta7Grubović Radica8Raka Florije9Jovanovska Viktorija10Todorovska Irena11Livrinova Vesna12Sima Aneta13Jovčevski Sasa14Milkovski Daniel15University Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaInstitute for Transfusion Medicine, Skopje, North MacedoniaInstitute for Transfusion Medicine, Skopje, North MacedoniaInstitute for Transfusion Medicine, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaInstitute for Transfusion Medicine, Skopje, North MacedoniaInstitute for Transfusion Medicine, Skopje, North MacedoniaInstitute for Transfusion Medicine, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaUniversity Clinic for Obstetrics and Gynaecology, Skopje, North MacedoniaInherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of a successful pregnancy outcome in a 37-year old woman with hypofibrinogenaemia. She was referred to a coagulation test in the first trimester because of history of preeclampsia and HELLP syndrome in previous pregnancy. Hypofibrinogenaemia was diagnosed with fibrinogen level of 0.7 g/L. During the pregnancy she was regularly monitored for fibrinogen levels and multiple cryoprecipitate concentrates were given. She delivered at 39th gestation week, with elective caesarean section under general anaesthesia. There was one episode of postpartum haemorrhage treated with 2 units of red blood cells, repeated infusions of cryoprecipitate to obtain the level of fibrinogen of 2 g/L. She was discharged on the 6th postpartum day in a good condition. In these disorders levels of fibrinogen should be higher than 1 g/L during pregnancy or 2 g/L in case of caesarean section for successful prenatal and peripartal management.https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2020/2490-33292002124S.pdfhypofibrinogenaemiapregnancyperipartal management |
| spellingShingle | Simeonova-Krstevska Slagjana Todorovska Elizabeta Makarovska-Bojadjieva Tatjana Petković Elena Stojčevski Saso Samardžiski Igor Spasovski Saso Dejanova Violeta Grubović Radica Raka Florije Jovanovska Viktorija Todorovska Irena Livrinova Vesna Sima Aneta Jovčevski Sasa Milkovski Daniel Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report Scripta Medica hypofibrinogenaemia pregnancy peripartal management |
| title | Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report |
| title_full | Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report |
| title_fullStr | Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report |
| title_full_unstemmed | Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report |
| title_short | Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report |
| title_sort | multidisciplinary approach to management of hypofibrinogenaemia in pregnancy a case report |
| topic | hypofibrinogenaemia pregnancy peripartal management |
| url | https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2020/2490-33292002124S.pdf |
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