Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study

Aim: The aim of this study was to evaluate the efficacy of various routinely used analgesics in the management of pulpal pain preoperatively. Materials and Methods: A total of 150 patients were randomly selected and divided into five groups each. At initial visit, a self-administered questionnaire w...

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Main Authors: Lavanya Thota, Rahul Bansal, Gunaranjan Thota, Meena Kumari Chikkanna, Hanan Shanab, Vinutha V Kumari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=684;epage=687;aulast=Thota
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author Lavanya Thota
Rahul Bansal
Gunaranjan Thota
Meena Kumari Chikkanna
Hanan Shanab
Vinutha V Kumari
author_facet Lavanya Thota
Rahul Bansal
Gunaranjan Thota
Meena Kumari Chikkanna
Hanan Shanab
Vinutha V Kumari
author_sort Lavanya Thota
collection DOAJ
description Aim: The aim of this study was to evaluate the efficacy of various routinely used analgesics in the management of pulpal pain preoperatively. Materials and Methods: A total of 150 patients were randomly selected and divided into five groups each. At initial visit, a self-administered questionnaire was given, and patients were asked to mark on the Visual Analog Scale (VAS) indicating severity of pain at that moment which is taken as a pretreatment VAS score. Group I patients received aceclofenac + paracetamol, Group II: ketorolac tromethamine, Group III: lornoxicam + paracetamol, Group IV: tramadol + paracetamol, and Group V: paracetamol. All the patients are requested to record their pain levels at 4 h, 6 h, 8 h, 24 h, and 48 h by means of VAS scores before and after treatment. Results: There was no significant decrease in frequency of pain when compared in the first three groups, whereas in Group III and Group IV, the patients experienced an effective reduction in pain because of sustained releasing ability of these drugs. Overall, there was no statistically significant differences among all the groups. Conclusion: This study suggests that there was no significant difference in reduction of pain preoperatively. However, lornoxicam + paracetamol and tramadol + paracetamol were effective because of their sustained releasing ability. Ketorolac was effective to reduce the pain for shorter duration. Paracetamol can be advised in compromised patients where safety is concerned.
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spelling doaj.art-b1157ac60d984e9cbd49d7fcbfec9d612022-12-21T18:42:43ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062021-01-0113568468710.4103/jpbs.JPBS_782_20Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical studyLavanya ThotaRahul BansalGunaranjan ThotaMeena Kumari ChikkannaHanan ShanabVinutha V KumariAim: The aim of this study was to evaluate the efficacy of various routinely used analgesics in the management of pulpal pain preoperatively. Materials and Methods: A total of 150 patients were randomly selected and divided into five groups each. At initial visit, a self-administered questionnaire was given, and patients were asked to mark on the Visual Analog Scale (VAS) indicating severity of pain at that moment which is taken as a pretreatment VAS score. Group I patients received aceclofenac + paracetamol, Group II: ketorolac tromethamine, Group III: lornoxicam + paracetamol, Group IV: tramadol + paracetamol, and Group V: paracetamol. All the patients are requested to record their pain levels at 4 h, 6 h, 8 h, 24 h, and 48 h by means of VAS scores before and after treatment. Results: There was no significant decrease in frequency of pain when compared in the first three groups, whereas in Group III and Group IV, the patients experienced an effective reduction in pain because of sustained releasing ability of these drugs. Overall, there was no statistically significant differences among all the groups. Conclusion: This study suggests that there was no significant difference in reduction of pain preoperatively. However, lornoxicam + paracetamol and tramadol + paracetamol were effective because of their sustained releasing ability. Ketorolac was effective to reduce the pain for shorter duration. Paracetamol can be advised in compromised patients where safety is concerned.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=684;epage=687;aulast=Thotaanalgesic time of total pain reliefpainpulpitistime of onset of action (tooad) of drug
spellingShingle Lavanya Thota
Rahul Bansal
Gunaranjan Thota
Meena Kumari Chikkanna
Hanan Shanab
Vinutha V Kumari
Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
Journal of Pharmacy and Bioallied Sciences
analgesic time of total pain relief
pain
pulpitis
time of onset of action (tooad) of drug
title Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
title_full Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
title_fullStr Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
title_full_unstemmed Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
title_short Efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
title_sort efficacy of routinely used analgesics in management of pulpal pain postoperatively a clinical study
topic analgesic time of total pain relief
pain
pulpitis
time of onset of action (tooad) of drug
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=684;epage=687;aulast=Thota
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