Is peripheral immunity regulated by blood-brain barrier permeability changes?

Is peripheral immunity regulated by blood-brain barrier permeability changes?

S100B is a reporter of blood-brain barrier (BBB) integrity which appears in blood when the BBB is breached. Circulating S100B derives from either extracranial sources or release into circulation by normal fluctuations in BBB integrity or pathologic BBB disruption (BBBD). Elevated S100B matches the c...

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Bibliographic Details
Main Authors: Erin Bargerstock, Vikram Puvenna, Philip Iffland, Tatiana Falcone, Mohammad Hossain, Stephen Vetter, Shumei Man, Leah Dickstein, Nicola Marchi, Chaitali Ghosh, Juliana Carvalho-Tavares, Damir Janigro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4079719?pdf=render

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