Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical a...

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Main Authors: Ligia J. Dominguez, Nicola Veronese, Laura Vernuccio, Giuseppina Catanese, Flora Inzerillo, Giuseppe Salemi, Mario Barbagallo
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/11/4080
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author Ligia J. Dominguez
Nicola Veronese
Laura Vernuccio
Giuseppina Catanese
Flora Inzerillo
Giuseppe Salemi
Mario Barbagallo
author_facet Ligia J. Dominguez
Nicola Veronese
Laura Vernuccio
Giuseppina Catanese
Flora Inzerillo
Giuseppe Salemi
Mario Barbagallo
author_sort Ligia J. Dominguez
collection DOAJ
description Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical activity. In the next decades, a rise in dementia cases is expected due largely to the aging of the world population. There are no hitherto effective pharmaceutical therapies to treat age-associated cognitive impairment and dementia, which underscores the crucial role of prevention. A relationship among diet, physical activity, and other lifestyle factors with cognitive function has been intensively studied with mounting evidence supporting the role of these determinants in the development of cognitive decline and dementia, which is a chief cause of disability globally. Several dietary patterns, foods, and nutrients have been investigated in this regard, with some encouraging and other disappointing results. This review presents the current evidence for the effects of dietary patterns, dietary components, some supplements, physical activity, sleep patterns, and social engagement on the prevention or delay of the onset of age-related cognitive decline and dementia.
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spelling doaj.art-b119fe1df7b043898768255341d543252023-11-23T00:50:20ZengMDPI AGNutrients2072-66432021-11-011311408010.3390/nu13114080Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and DementiaLigia J. Dominguez0Nicola Veronese1Laura Vernuccio2Giuseppina Catanese3Flora Inzerillo4Giuseppe Salemi5Mario Barbagallo6Geriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, ItalyGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, ItalyGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, ItalyGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, ItalyGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, ItalyDepartment of Biomedicine, Neuroscience, and Advanced Diagnostics, University of Palermo, 90100 Palermo, ItalyGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, ItalyMultiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical activity. In the next decades, a rise in dementia cases is expected due largely to the aging of the world population. There are no hitherto effective pharmaceutical therapies to treat age-associated cognitive impairment and dementia, which underscores the crucial role of prevention. A relationship among diet, physical activity, and other lifestyle factors with cognitive function has been intensively studied with mounting evidence supporting the role of these determinants in the development of cognitive decline and dementia, which is a chief cause of disability globally. Several dietary patterns, foods, and nutrients have been investigated in this regard, with some encouraging and other disappointing results. This review presents the current evidence for the effects of dietary patterns, dietary components, some supplements, physical activity, sleep patterns, and social engagement on the prevention or delay of the onset of age-related cognitive decline and dementia.https://www.mdpi.com/2072-6643/13/11/4080cognitive declineAlzheimerdementiaagingnutritionphysical activity
spellingShingle Ligia J. Dominguez
Nicola Veronese
Laura Vernuccio
Giuseppina Catanese
Flora Inzerillo
Giuseppe Salemi
Mario Barbagallo
Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
Nutrients
cognitive decline
Alzheimer
dementia
aging
nutrition
physical activity
title Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
title_full Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
title_fullStr Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
title_full_unstemmed Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
title_short Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia
title_sort nutrition physical activity and other lifestyle factors in the prevention of cognitive decline and dementia
topic cognitive decline
Alzheimer
dementia
aging
nutrition
physical activity
url https://www.mdpi.com/2072-6643/13/11/4080
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