Haloperidol affects bones while clozapine alters metabolic parameters - sex specific effects in rats perinatally treated with phencyclidine

Haloperidol affects bones while clozapine alters metabolic parameters - sex specific effects in rats perinatally treated with phencyclidine

Abstract Background The presentation of schizophrenia (SCH) symptoms differs between the sexes. Long-term treatment with antipsychotics is frequently associated with decreased bone mineral density, increased fracture risk and metabolic side effects. Perinatal phencyclidine (PCP) administration to ro...

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Détails bibliographiques
Auteurs principaux: Tatjana Nikolić, Milan Petronijević, Jelena Sopta, Milica Velimirović, Tihomir Stojković, Gordana Jevtić Dožudić, Milan Aksić, Nevena V. Radonjić, Nataša Petronijević
Format: Article
Langue:English
Publié: BMC 2017-10-01
Collection:BMC Pharmacology and Toxicology
Sujets:
Schizophrenia
Bone mineral density
Haloperidol
Clozapine
Corticosterone
Phencyclidine
Accès en ligne:http://link.springer.com/article/10.1186/s40360-017-0171-4

Internet

http://link.springer.com/article/10.1186/s40360-017-0171-4

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