A Novel Controlled PTEN-Knockout Mouse Model for Prostate Cancer Study

A Novel Controlled PTEN-Knockout Mouse Model for Prostate Cancer Study

Prostate cancer (PCa) is associated with advanced age, but how age contributes to prostate carcinogenesis remains unknown. The prostate-specific Pten conditional knockout mouse model closely imitates human PCa initiation and progression. To better understand how age impacts PCa in an experimental mo...

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Bibliographic Details
Main Authors: Sen Liu, Bing Zhang, Brian G. Rowan, S. Michal Jazwinski, Asim B. Abdel-Mageed, Chad Steele, Alun R. Wang, Oliver Sartor, Tianhua Niu, Qiuyang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
cre-expressing adenovirus
age
prostate cancer
Pten
mouse models
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.696537/full

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