The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study
Abstract Background Few studies assess the link between plant-based diets and colorectal cancer (CRC) incidence. To our knowledge, no study has examined the association between pro-vegetarian dietary pattern (PDP) and CRC globally or among Iranians. Therefore, the objective of our matched case-contr...
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | BMC Research Notes |
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| Online Access: | https://doi.org/10.1186/s13104-023-06606-6 |
| _version_ | 1827764673317961728 |
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| author | Elham Tavassoli Nejad Elham Moslemi Fateme Souni Marzieh Mahmoodi Mohebat Vali Mohammad Vatanpour Mehran Nouri Atena Ramezani Zainab Shateri Bahram Rashidkhani |
| author_facet | Elham Tavassoli Nejad Elham Moslemi Fateme Souni Marzieh Mahmoodi Mohebat Vali Mohammad Vatanpour Mehran Nouri Atena Ramezani Zainab Shateri Bahram Rashidkhani |
| author_sort | Elham Tavassoli Nejad |
| collection | DOAJ |
| description | Abstract Background Few studies assess the link between plant-based diets and colorectal cancer (CRC) incidence. To our knowledge, no study has examined the association between pro-vegetarian dietary pattern (PDP) and CRC globally or among Iranians. Therefore, the objective of our matched case-control study was to evaluate the association between PDP and CRC in the Iranian population. Methods The present research was a hospital-based case (n = 71)-control (n = 142) study conducted in the same hospitals in Tehran, Iran. This study used a reliable and valid semi-quantitative food frequency questionnaire to evaluate the participants’ dietary intake. According to the residual method, the selected plant and animal foods have been adjusted in the total energy intake to calculate the PDP index. Odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for confounding variables were also expressed using logistic regression by SPSS software. Results In the crude and adjusted models, we observed that the odds of CRC decreased significantly in the 3rd and last quartile of PDP compared to the 1st quartile (Q) (Crude model: Q3: OR = 0.36, 95% CI: 0.17 − 0.79, P-value = 0.011 and Q4: OR = 0.33, 95% CI: 0.14 − 0.79, P-value = 0.012 - Adjusted model: Q3: OR = 0.41, 95% CI: 0.18 − 0.94, P-value = 0.035 and Q4: OR = 0.35, 95% CI: 0.14 − 0.87, P-value = 0.025). Conclusions Based on the results of the present case-control study in the Iranian population, it was concluded that PDP, which involves consuming vegetables, fruits, cereals, dairy products, and low meat consumption, reduces the odds of CRC. In conclusion, adherence to PDP is associated with a decreased odds of CRC. |
| first_indexed | 2024-03-11T11:08:42Z |
| format | Article |
| id | doaj.art-b11bdc143ef141c8a4a02122498eb718 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-03-11T11:08:42Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-b11bdc143ef141c8a4a02122498eb7182023-11-12T12:05:34ZengBMCBMC Research Notes1756-05002023-11-011611810.1186/s13104-023-06606-6The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control studyElham Tavassoli Nejad0Elham Moslemi1Fateme Souni2Marzieh Mahmoodi3Mohebat Vali4Mohammad Vatanpour5Mehran Nouri6Atena Ramezani7Zainab Shateri8Bahram Rashidkhani9Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical SciencesStudent Research Committee, Faculty of Nutrition and Food Sciences, Tabriz University of Medical SciencesDepartment of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical SciencesNutrition Research Center, Shiraz University of Medical SciencesStudent Research Committee, Shiraz University of Medical SciencesDepartment of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical SciencesDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical SciencesDiabetes Research Center, Mazandaran University of Medical SciencesStudent Research Committee, Ahvaz Jundishapur University of Medical SciencesDepartment of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical SciencesAbstract Background Few studies assess the link between plant-based diets and colorectal cancer (CRC) incidence. To our knowledge, no study has examined the association between pro-vegetarian dietary pattern (PDP) and CRC globally or among Iranians. Therefore, the objective of our matched case-control study was to evaluate the association between PDP and CRC in the Iranian population. Methods The present research was a hospital-based case (n = 71)-control (n = 142) study conducted in the same hospitals in Tehran, Iran. This study used a reliable and valid semi-quantitative food frequency questionnaire to evaluate the participants’ dietary intake. According to the residual method, the selected plant and animal foods have been adjusted in the total energy intake to calculate the PDP index. Odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for confounding variables were also expressed using logistic regression by SPSS software. Results In the crude and adjusted models, we observed that the odds of CRC decreased significantly in the 3rd and last quartile of PDP compared to the 1st quartile (Q) (Crude model: Q3: OR = 0.36, 95% CI: 0.17 − 0.79, P-value = 0.011 and Q4: OR = 0.33, 95% CI: 0.14 − 0.79, P-value = 0.012 - Adjusted model: Q3: OR = 0.41, 95% CI: 0.18 − 0.94, P-value = 0.035 and Q4: OR = 0.35, 95% CI: 0.14 − 0.87, P-value = 0.025). Conclusions Based on the results of the present case-control study in the Iranian population, it was concluded that PDP, which involves consuming vegetables, fruits, cereals, dairy products, and low meat consumption, reduces the odds of CRC. In conclusion, adherence to PDP is associated with a decreased odds of CRC.https://doi.org/10.1186/s13104-023-06606-6Pro-vegetarian dietary patternColorectal NeoplasmsColorectal cancerIranian |
| spellingShingle | Elham Tavassoli Nejad Elham Moslemi Fateme Souni Marzieh Mahmoodi Mohebat Vali Mohammad Vatanpour Mehran Nouri Atena Ramezani Zainab Shateri Bahram Rashidkhani The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study BMC Research Notes Pro-vegetarian dietary pattern Colorectal Neoplasms Colorectal cancer Iranian |
| title | The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study |
| title_full | The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study |
| title_fullStr | The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study |
| title_full_unstemmed | The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study |
| title_short | The association between pro-vegetarian dietary pattern and risk of colorectal cancer: a matched case-control study |
| title_sort | association between pro vegetarian dietary pattern and risk of colorectal cancer a matched case control study |
| topic | Pro-vegetarian dietary pattern Colorectal Neoplasms Colorectal cancer Iranian |
| url | https://doi.org/10.1186/s13104-023-06606-6 |
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