Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients
It is suggested that adipocytokines secreted by adipose tissue play a role in the development of obesity-related complications and diabetes. Regular aerobic exercise has been shown to reduce the risk of metabolic complications in obese type 2 diabetic subjects. The aim of this study was to compare t...
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| Format: | Article |
| Language: | English |
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Elsevier
2011-04-01
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| Series: | Journal of Advanced Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2090123210001104 |
| _version_ | 1819081624289017856 |
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| author | Shehab M. Abd El-Kader |
| author_facet | Shehab M. Abd El-Kader |
| author_sort | Shehab M. Abd El-Kader |
| collection | DOAJ |
| description | It is suggested that adipocytokines secreted by adipose tissue play a role in the development of obesity-related complications and diabetes. Regular aerobic exercise has been shown to reduce the risk of metabolic complications in obese type 2 diabetic subjects. The aim of this study was to compare the impact of aerobic versus resistance training on insulin resistance, adipocytokines and inflammatory cytokine in obese type 2 diabetic patients. Forty obese type 2 diabetic patients of both sexes with body mass index (BMI) ranging from 31 to 35 kg/m2, non smokers, and free from respiratory, kidney, liver, metabolic and neurological disorders, were selected for this study. Their ages ranged from 34 to 56 years. The subjects were divided into two equal groups: the first group received aerobic exercise training. The second group (B) received resisted exercise training three times a week for three months. The mean values of tumour necrosis factor-α (TNF-α), interleukin (IL-6), Assessment-Insulin Resistance (HOMA) index for insulin sensitivity and glycosylated hemoglobin (HBA1c), were significantly decreased in both groups. Also, there was a significant difference between the groups after treatment on all measured variables. It is suggested that in obese type 2 diabetic patients aerobic exercise is more appropriate for modulating insulin resistance, adipocytokines and inflammatory cytokine levels than is resisted exercise training. |
| first_indexed | 2024-12-21T20:03:44Z |
| format | Article |
| id | doaj.art-b11f747f4a954e898598835ad0b5a4a4 |
| institution | Directory Open Access Journal |
| issn | 2090-1232 2090-1224 |
| language | English |
| last_indexed | 2024-12-21T20:03:44Z |
| publishDate | 2011-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Advanced Research |
| spelling | doaj.art-b11f747f4a954e898598835ad0b5a4a42022-12-21T18:51:54ZengElsevierJournal of Advanced Research2090-12322090-12242011-04-012217918310.1016/j.jare.2010.09.003Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patientsShehab M. Abd El-KaderIt is suggested that adipocytokines secreted by adipose tissue play a role in the development of obesity-related complications and diabetes. Regular aerobic exercise has been shown to reduce the risk of metabolic complications in obese type 2 diabetic subjects. The aim of this study was to compare the impact of aerobic versus resistance training on insulin resistance, adipocytokines and inflammatory cytokine in obese type 2 diabetic patients. Forty obese type 2 diabetic patients of both sexes with body mass index (BMI) ranging from 31 to 35 kg/m2, non smokers, and free from respiratory, kidney, liver, metabolic and neurological disorders, were selected for this study. Their ages ranged from 34 to 56 years. The subjects were divided into two equal groups: the first group received aerobic exercise training. The second group (B) received resisted exercise training three times a week for three months. The mean values of tumour necrosis factor-α (TNF-α), interleukin (IL-6), Assessment-Insulin Resistance (HOMA) index for insulin sensitivity and glycosylated hemoglobin (HBA1c), were significantly decreased in both groups. Also, there was a significant difference between the groups after treatment on all measured variables. It is suggested that in obese type 2 diabetic patients aerobic exercise is more appropriate for modulating insulin resistance, adipocytokines and inflammatory cytokine levels than is resisted exercise training.http://www.sciencedirect.com/science/article/pii/S2090123210001104Aerobic exerciseResistance exerciseInsulin resistanceAdipocytokinesInflammatory cytokineObesity |
| spellingShingle | Shehab M. Abd El-Kader Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients Journal of Advanced Research Aerobic exercise Resistance exercise Insulin resistance Adipocytokines Inflammatory cytokine Obesity |
| title | Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients |
| title_full | Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients |
| title_fullStr | Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients |
| title_full_unstemmed | Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients |
| title_short | Aerobic versus resistance exercise training in modulation of insulin resistance, adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients |
| title_sort | aerobic versus resistance exercise training in modulation of insulin resistance adipocytokines and inflammatory cytokine levels in obese type 2 diabetic patients |
| topic | Aerobic exercise Resistance exercise Insulin resistance Adipocytokines Inflammatory cytokine Obesity |
| url | http://www.sciencedirect.com/science/article/pii/S2090123210001104 |
| work_keys_str_mv | AT shehabmabdelkader aerobicversusresistanceexercisetraininginmodulationofinsulinresistanceadipocytokinesandinflammatorycytokinelevelsinobesetype2diabeticpatients |