Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite
This study describes the electrochemical preparation of the electrocatalytic oxidation/reduction of noradrenaline in modified glassy carbon of cobalt ferrite nanoparticles and carbon nanotubes (GC/MWCNT/FCo98). The cobalt ferrite powder was characterized by X-ray diffraction (XRD) and transmission e...
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MDPI AG
2018-04-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/18/4/1223 |
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| author | Daniely Ferreira de Queiroz Tony Rogério de Lima Dadamos Sergio Antonio Spinola Machado Marco Antonio Utrera Martines |
| author_facet | Daniely Ferreira de Queiroz Tony Rogério de Lima Dadamos Sergio Antonio Spinola Machado Marco Antonio Utrera Martines |
| author_sort | Daniely Ferreira de Queiroz |
| collection | DOAJ |
| description | This study describes the electrochemical preparation of the electrocatalytic oxidation/reduction of noradrenaline in modified glassy carbon of cobalt ferrite nanoparticles and carbon nanotubes (GC/MWCNT/FCo98). The cobalt ferrite powder was characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The optimum conditions found in an electrode composition were 4 μL of cobalt ferrite and 10 μL of carbon nanotubes in 0.1 mol L−1 PBS at pH 7.0. The electrode displays electrochemical behavior in a wide potential range (−0.4 to 1.0 V vs. Ag/AgCl), high conductivity, and electrode stability/durability in 0.1 mol L−1 PBS. Catalytic oxidation of noradrenaline was performed at the unmodified GC electrode at +0.60 V vs. Ag/AgCl and current of 0.17 μA and modified GC with cobalt ferrite nanoparticles and carbon nanotubes at +0.54 V vs. Ag/AgCl and current of 0.23 mA. With regard to the anodic peak current (Ipa) versus noradrenaline concentration by means of the amperometric method at the modified electrode, (which is linear in the 0.16 and 1.91 mmol L−1 concentration range), the concentration limit was 0.76 μmol L−1. In this way, the modified electrode GC/MWCNT/FCo98 was found to be a promising application for the determination of this neurotransmitter in the area of neuroscience. |
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| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T12:58:35Z |
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| spelling | doaj.art-b128ebaf0fe34d10a4201a1345d11f522022-12-22T04:23:01ZengMDPI AGSensors1424-82202018-04-01184122310.3390/s18041223s18041223Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt FerriteDaniely Ferreira de Queiroz0Tony Rogério de Lima Dadamos1Sergio Antonio Spinola Machado2Marco Antonio Utrera Martines3Laboratório de Materiais Coloidais, Departamento de Físico Química, Instituto de Química, Universidade de São Paulo, Av. Trabalhador São Carlense, C.P. 780, São Carlos 13560-970, SP, BrazilInstituto de Biociências, Letras e Ciências Exatas, Campus de São José do Rio Preto, Universidade Estadual Paulista, R. Cristóvão Colombo, 2265, Jardim Nazareth, São José do Rio Preto 15054-000, SP, BrazilLaboratório de Materiais Coloidais, Departamento de Físico Química, Instituto de Química, Universidade de São Paulo, Av. Trabalhador São Carlense, C.P. 780, São Carlos 13560-970, SP, BrazilLaboratório de Química de Superfície e Moléculas Bioativas, Departamento de Química, Universidade Federal do Mato Grosso do Sul, Av. Senador Filinto Müller, 1555, Campo Grande 79074-460, MS, BrazilThis study describes the electrochemical preparation of the electrocatalytic oxidation/reduction of noradrenaline in modified glassy carbon of cobalt ferrite nanoparticles and carbon nanotubes (GC/MWCNT/FCo98). The cobalt ferrite powder was characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The optimum conditions found in an electrode composition were 4 μL of cobalt ferrite and 10 μL of carbon nanotubes in 0.1 mol L−1 PBS at pH 7.0. The electrode displays electrochemical behavior in a wide potential range (−0.4 to 1.0 V vs. Ag/AgCl), high conductivity, and electrode stability/durability in 0.1 mol L−1 PBS. Catalytic oxidation of noradrenaline was performed at the unmodified GC electrode at +0.60 V vs. Ag/AgCl and current of 0.17 μA and modified GC with cobalt ferrite nanoparticles and carbon nanotubes at +0.54 V vs. Ag/AgCl and current of 0.23 mA. With regard to the anodic peak current (Ipa) versus noradrenaline concentration by means of the amperometric method at the modified electrode, (which is linear in the 0.16 and 1.91 mmol L−1 concentration range), the concentration limit was 0.76 μmol L−1. In this way, the modified electrode GC/MWCNT/FCo98 was found to be a promising application for the determination of this neurotransmitter in the area of neuroscience.http://www.mdpi.com/1424-8220/18/4/1223electrode modifiedcobalt ferritenoradrenaline |
| spellingShingle | Daniely Ferreira de Queiroz Tony Rogério de Lima Dadamos Sergio Antonio Spinola Machado Marco Antonio Utrera Martines Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite Sensors electrode modified cobalt ferrite noradrenaline |
| title | Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite |
| title_full | Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite |
| title_fullStr | Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite |
| title_full_unstemmed | Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite |
| title_short | Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite |
| title_sort | electrochemical determination of norepinephrine by means of modified glassy carbon electrodes with carbon nanotubes and magnetic nanoparticles of cobalt ferrite |
| topic | electrode modified cobalt ferrite noradrenaline |
| url | http://www.mdpi.com/1424-8220/18/4/1223 |
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