Neonatal maternal separation increases susceptibility to experimental colitis and acute stress exposure in male mice

Neonatal maternal separation increases susceptibility to experimental colitis and acute stress exposure in male mice

Experiencing early life stress can result in maladjusted stress response via dysregulation of the hypothalamic-pituitary-adrenal axis and serves as a risk factor for developing chronic pelvic pain disorders. We investigated whether neonatal maternal separation (NMS) would increase susceptibility to...

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Bibliographic Details
Main Authors: Isabella M. Fuentes, Natalie K. Walker, Angela N. Pierce, Briana R. Holt, Elizabeth R. Di Silvestro, Julie A. Christianson
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:IBRO Reports
Subjects:
Colorectal distension
Experimental colitis
Maternal separation
Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2451830116300048

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