Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous system diseases characterized by the degeneration of lower motor neurons. They share a number of additional pathological, cellular, and genetic parallels suggesting that mechanistic and clinical insights into on...

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Detaylı Bibliyografya
Asıl Yazarlar: Andrew P. Tosolini, James N. Sleigh
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017-12-01
Seri Bilgileri:Frontiers in Molecular Neuroscience
Konular:
Online Erişim:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00405/full