Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous system diseases characterized by the degeneration of lower motor neurons. They share a number of additional pathological, cellular, and genetic parallels suggesting that mechanistic and clinical insights into on...

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Váldodahkkit: Andrew P. Tosolini, James N. Sleigh
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Frontiers Media S.A. 2017-12-01
Ráidu:Frontiers in Molecular Neuroscience
Fáttát:
Liŋkkat:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00405/full