Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous system diseases characterized by the degeneration of lower motor neurons. They share a number of additional pathological, cellular, and genetic parallels suggesting that mechanistic and clinical insights into on...

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书目详细资料
Main Authors: Andrew P. Tosolini, James N. Sleigh
格式: 文件
语言:English
出版: Frontiers Media S.A. 2017-12-01
丛编:Frontiers in Molecular Neuroscience
主题:
在线阅读:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00405/full