Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study

Background and study aims Endoscopic treatment of Zenker’s diverticulum has proven feasible, but electrocautery and CO2 laser technology carry the risk of collateral thermal injury. Thulium laser septum incision may overcome this limitation. We describe for the first time the use of thulium laser th...

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Main Authors: Stefano Siboni, Alberto Aiolfi, Chiara Ceriani, Gian Eugenio Tontini, Luigi Bonavina
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-03-01
Series:Endoscopy International Open
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-0581-8789
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author Stefano Siboni
Alberto Aiolfi
Chiara Ceriani
Gian Eugenio Tontini
Luigi Bonavina
author_facet Stefano Siboni
Alberto Aiolfi
Chiara Ceriani
Gian Eugenio Tontini
Luigi Bonavina
author_sort Stefano Siboni
collection DOAJ
description Background and study aims Endoscopic treatment of Zenker’s diverticulum has proven feasible, but electrocautery and CO2 laser technology carry the risk of collateral thermal injury. Thulium laser septum incision may overcome this limitation. We describe for the first time the use of thulium laser through flexible endoscopy in a small cohort of patients with Zenker diverticulum. Patients and methods Thulium laser septum division was performed via flexible endoscopy under general anesthesia in consecutive symptomatic patients with primary or recurrent Zenker diverticulum. Primary study outcomes were feasibility and safety of the procedure. A 1.9-μm laser fiber was used with an emission power of 10 – 16 W. Results Five patients were treated between May and June 2017. Two patients presented with recurrent symptomatic diverticulum after previous transoral septum stapling. Complete division of the septum was achieved in all patients. There was no bleeding nor need of adjunctive electrocautery devices to complete the procedure. The postoperative course was uneventful in all patients; the chest film and gastrographin swallow study on postoperative Day 1 were negative for pneumomediastinum, leaks or residual pouch. All patients were discharged within 48 hours on a soft diet. At the 1- and 3-month follow-up visits, all patients were satisfied with the procedure and reported improved swallowing and absence of regurgitation and cough. Conclusions Division of Zenker’s septum with thulium laser is feasible and safe through flexible endoscopy. Longer-term follow-up is required to establish efficacy and effectiveness of this novel procedure.
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spelling doaj.art-b12c151b09004836b913b818c833f27e2022-12-22T02:44:18ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362018-03-010604E470E47310.1055/a-0581-8789Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept studyStefano Siboni0Alberto Aiolfi1Chiara Ceriani2Gian Eugenio Tontini3Luigi Bonavina4University of Milan, Department of Biomedical Sciences for Health, Division of General Surgery, IRCCS Policlinico San Donato, Milan, ItalyUniversity of Milan, Department of Biomedical Sciences for Health, Division of General Surgery, IRCCS Policlinico San Donato, Milan, ItalyUniversity of Milan, Department of Biomedical Sciences for Health, Division of General Surgery, IRCCS Policlinico San Donato, Milan, ItalyUniversity of Milan, Department of Biomedical Sciences for Health, Division of General Surgery, IRCCS Policlinico San Donato, Milan, ItalyUniversity of Milan, Department of Biomedical Sciences for Health, Division of General Surgery, IRCCS Policlinico San Donato, Milan, ItalyBackground and study aims Endoscopic treatment of Zenker’s diverticulum has proven feasible, but electrocautery and CO2 laser technology carry the risk of collateral thermal injury. Thulium laser septum incision may overcome this limitation. We describe for the first time the use of thulium laser through flexible endoscopy in a small cohort of patients with Zenker diverticulum. Patients and methods Thulium laser septum division was performed via flexible endoscopy under general anesthesia in consecutive symptomatic patients with primary or recurrent Zenker diverticulum. Primary study outcomes were feasibility and safety of the procedure. A 1.9-μm laser fiber was used with an emission power of 10 – 16 W. Results Five patients were treated between May and June 2017. Two patients presented with recurrent symptomatic diverticulum after previous transoral septum stapling. Complete division of the septum was achieved in all patients. There was no bleeding nor need of adjunctive electrocautery devices to complete the procedure. The postoperative course was uneventful in all patients; the chest film and gastrographin swallow study on postoperative Day 1 were negative for pneumomediastinum, leaks or residual pouch. All patients were discharged within 48 hours on a soft diet. At the 1- and 3-month follow-up visits, all patients were satisfied with the procedure and reported improved swallowing and absence of regurgitation and cough. Conclusions Division of Zenker’s septum with thulium laser is feasible and safe through flexible endoscopy. Longer-term follow-up is required to establish efficacy and effectiveness of this novel procedure.http://www.thieme-connect.de/DOI/DOI?10.1055/a-0581-8789
spellingShingle Stefano Siboni
Alberto Aiolfi
Chiara Ceriani
Gian Eugenio Tontini
Luigi Bonavina
Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study
Endoscopy International Open
title Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study
title_full Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study
title_fullStr Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study
title_full_unstemmed Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study
title_short Cricopharyngeal myotomy with thulium laser through flexible endoscopy: proof-of-concept study
title_sort cricopharyngeal myotomy with thulium laser through flexible endoscopy proof of concept study
url http://www.thieme-connect.de/DOI/DOI?10.1055/a-0581-8789
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