Implications for COVID-19 vaccine uptake: A systematic review

Background: Globally, increasing coronavirus disease (COVID-19) vaccination coverage remains a major public health concern in the face of high rates of COVID-19 hesitancy among the general population. We must understand the impact of the determinants of COVID-19 vaccine uptake when designing nationa...

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Main Authors: Peter Adu, Tosin Poopola, Oleg N. Medvedev, Sunny Collings, James Mbinta, Clive Aspin, Colin R. Simpson
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Infection and Public Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034123000308
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author Peter Adu
Tosin Poopola
Oleg N. Medvedev
Sunny Collings
James Mbinta
Clive Aspin
Colin R. Simpson
author_facet Peter Adu
Tosin Poopola
Oleg N. Medvedev
Sunny Collings
James Mbinta
Clive Aspin
Colin R. Simpson
author_sort Peter Adu
collection DOAJ
description Background: Globally, increasing coronavirus disease (COVID-19) vaccination coverage remains a major public health concern in the face of high rates of COVID-19 hesitancy among the general population. We must understand the impact of the determinants of COVID-19 vaccine uptake when designing national vaccination programmes. We aimed to synthesise nationwide evidence regarding COVID-19 infodemics and the demographic, psychological, and social predictors of COVID-19 vaccination uptake. Methods: We systematically searched seven databases between July 2021 and March 2022 to retrieve relevant articles published since COVID-19 was first reported on 31 December 2019 in Wuhan, China. Of the 12,502 peer-reviewed articles retrieved from the databases, 57 met the selection criteria and were included in this systematic review. We explored COVID-19 vaccine uptake determinants before and after the first COVID-19 vaccine roll-out by the Food and Drug Authority (FDA). Results: Increased COVID-19 vaccine uptake rates were associated with decreased hesitancy. Concerns about COVID-19 vaccine safety, negative side effects, rapid development of the COVID-19 vaccine, and uncertainty about vaccine effectiveness were associated with reluctance to be vaccinated. After the US FDA approval of COVID-19 vaccines, phobia of medical procedures such as vaccine injection and inadequate information about vaccines were the main determinants of COVID-19 vaccine hesitancy. Conclusion: Addressing effectiveness and safety concerns regarding COVID-19 vaccines, as well as providing adequate information about vaccines and the impacts of pandemics, should be considered before implementation of any vaccination programme. Reassuring people about the safety of medical vaccination and using alternative procedures such as needle-free vaccination may help further increase vaccination uptake.
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spelling doaj.art-b12c7ab8e60340f7aca92ec2252435bc2023-02-18T04:16:42ZengElsevierJournal of Infection and Public Health1876-03412023-03-01163441466Implications for COVID-19 vaccine uptake: A systematic reviewPeter Adu0Tosin Poopola1Oleg N. Medvedev2Sunny Collings3James Mbinta4Clive Aspin5Colin R. Simpson6School of Health, Wellington Faculty of Health, Victoria University of Wellington, New Zealand; Correspondence to: Victoria University of Wellington, P. O. Box 600, Wellington 6140, New Zealand.School of Health, Wellington Faculty of Health, Victoria University of Wellington, New ZealandUniversity of Waikato, New ZealandSchool of Health, Wellington Faculty of Health, Victoria University of Wellington, New ZealandSchool of Health, Wellington Faculty of Health, Victoria University of Wellington, New ZealandSchool of Health, Wellington Faculty of Health, Victoria University of Wellington, New ZealandSchool of Health, Wellington Faculty of Health, Victoria University of Wellington, New ZealandBackground: Globally, increasing coronavirus disease (COVID-19) vaccination coverage remains a major public health concern in the face of high rates of COVID-19 hesitancy among the general population. We must understand the impact of the determinants of COVID-19 vaccine uptake when designing national vaccination programmes. We aimed to synthesise nationwide evidence regarding COVID-19 infodemics and the demographic, psychological, and social predictors of COVID-19 vaccination uptake. Methods: We systematically searched seven databases between July 2021 and March 2022 to retrieve relevant articles published since COVID-19 was first reported on 31 December 2019 in Wuhan, China. Of the 12,502 peer-reviewed articles retrieved from the databases, 57 met the selection criteria and were included in this systematic review. We explored COVID-19 vaccine uptake determinants before and after the first COVID-19 vaccine roll-out by the Food and Drug Authority (FDA). Results: Increased COVID-19 vaccine uptake rates were associated with decreased hesitancy. Concerns about COVID-19 vaccine safety, negative side effects, rapid development of the COVID-19 vaccine, and uncertainty about vaccine effectiveness were associated with reluctance to be vaccinated. After the US FDA approval of COVID-19 vaccines, phobia of medical procedures such as vaccine injection and inadequate information about vaccines were the main determinants of COVID-19 vaccine hesitancy. Conclusion: Addressing effectiveness and safety concerns regarding COVID-19 vaccines, as well as providing adequate information about vaccines and the impacts of pandemics, should be considered before implementation of any vaccination programme. Reassuring people about the safety of medical vaccination and using alternative procedures such as needle-free vaccination may help further increase vaccination uptake.http://www.sciencedirect.com/science/article/pii/S1876034123000308Vaccine uptakeCOVID-19VaccinationHesitancyInfodemics
spellingShingle Peter Adu
Tosin Poopola
Oleg N. Medvedev
Sunny Collings
James Mbinta
Clive Aspin
Colin R. Simpson
Implications for COVID-19 vaccine uptake: A systematic review
Journal of Infection and Public Health
Vaccine uptake
COVID-19
Vaccination
Hesitancy
Infodemics
title Implications for COVID-19 vaccine uptake: A systematic review
title_full Implications for COVID-19 vaccine uptake: A systematic review
title_fullStr Implications for COVID-19 vaccine uptake: A systematic review
title_full_unstemmed Implications for COVID-19 vaccine uptake: A systematic review
title_short Implications for COVID-19 vaccine uptake: A systematic review
title_sort implications for covid 19 vaccine uptake a systematic review
topic Vaccine uptake
COVID-19
Vaccination
Hesitancy
Infodemics
url http://www.sciencedirect.com/science/article/pii/S1876034123000308
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