A potential marker DYF371 for differentiating han population from non-han population in Chinese
DYF371 locus and single-nucleotide polymorphisms (SNPs) defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals, including 90 Han population and 52 minorities. In total, 37 SNP-short tandem repeat haplotypes were detected. Nine of these 37 haplotypes wer...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Forensic Science and Medicine |
| Subjects: | |
| Online Access: | http://www.jfsmonline.com/article.asp?issn=2349-5014;year=2020;volume=6;issue=1;spage=1;epage=4;aulast=Nan |
| _version_ | 1818390245136138240 |
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| author | Hailun Nan Dejian Lu |
| author_facet | Hailun Nan Dejian Lu |
| author_sort | Hailun Nan |
| collection | DOAJ |
| description | DYF371 locus and single-nucleotide polymorphisms (SNPs) defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals, including 90 Han population and 52 minorities. In total, 37 SNP-short tandem repeat haplotypes were detected. Nine of these 37 haplotypes were unique (24.32%). The gene diversity and discrimination capacity values are 0.8321 and 0.2606, respectively. Furthermore, only five males (5.55%) in the Han samples were determined that they had one copy of allele with SNP T-type and three copies of alleles with SNP C-types, whereas 14 individuals (26.92%) were observed in minorities' samples. The genotype proportion comprising three distinguishing copies of the allele with SNP C-types in Han sample was greatly lower than that in the sample of minorities. Similar results were shown for allele 11C and 10C. Therefore, the alleles of DYF371 with SNP C-type have the potential to differentiate the Han and non-Han Chinese populations. |
| first_indexed | 2024-12-14T04:54:33Z |
| format | Article |
| id | doaj.art-b13258a4aca94057b100d2a89282e281 |
| institution | Directory Open Access Journal |
| issn | 2349-5014 |
| language | English |
| last_indexed | 2024-12-14T04:54:33Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
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| series | Journal of Forensic Science and Medicine |
| spelling | doaj.art-b13258a4aca94057b100d2a89282e2812022-12-21T23:16:25ZengWolters Kluwer Medknow PublicationsJournal of Forensic Science and Medicine2349-50142020-01-01611410.4103/1735-3327.280892A potential marker DYF371 for differentiating han population from non-han population in ChineseHailun NanDejian LuDYF371 locus and single-nucleotide polymorphisms (SNPs) defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals, including 90 Han population and 52 minorities. In total, 37 SNP-short tandem repeat haplotypes were detected. Nine of these 37 haplotypes were unique (24.32%). The gene diversity and discrimination capacity values are 0.8321 and 0.2606, respectively. Furthermore, only five males (5.55%) in the Han samples were determined that they had one copy of allele with SNP T-type and three copies of alleles with SNP C-types, whereas 14 individuals (26.92%) were observed in minorities' samples. The genotype proportion comprising three distinguishing copies of the allele with SNP C-types in Han sample was greatly lower than that in the sample of minorities. Similar results were shown for allele 11C and 10C. Therefore, the alleles of DYF371 with SNP C-type have the potential to differentiate the Han and non-Han Chinese populations.http://www.jfsmonline.com/article.asp?issn=2349-5014;year=2020;volume=6;issue=1;spage=1;epage=4;aulast=Nandyf371multi-copymultiplex polymerase chain reactionsingle-nucleotide polymorphismpolymorphism-short tandem repeat |
| spellingShingle | Hailun Nan Dejian Lu A potential marker DYF371 for differentiating han population from non-han population in Chinese Journal of Forensic Science and Medicine dyf371 multi-copy multiplex polymerase chain reaction single-nucleotide polymorphism polymorphism-short tandem repeat |
| title | A potential marker DYF371 for differentiating han population from non-han population in Chinese |
| title_full | A potential marker DYF371 for differentiating han population from non-han population in Chinese |
| title_fullStr | A potential marker DYF371 for differentiating han population from non-han population in Chinese |
| title_full_unstemmed | A potential marker DYF371 for differentiating han population from non-han population in Chinese |
| title_short | A potential marker DYF371 for differentiating han population from non-han population in Chinese |
| title_sort | potential marker dyf371 for differentiating han population from non han population in chinese |
| topic | dyf371 multi-copy multiplex polymerase chain reaction single-nucleotide polymorphism polymorphism-short tandem repeat |
| url | http://www.jfsmonline.com/article.asp?issn=2349-5014;year=2020;volume=6;issue=1;spage=1;epage=4;aulast=Nan |
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