Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare, rapidly progressive, and often fatal complication of cancer, particularly prostate cancer. A 67-year-old man with advanced prostate cancer developed dyspnea. Chest computed tomography revealed ground-glass opacities across bilateral lung f...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-03-01
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| Series: | Urology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221444201930419X |
| _version_ | 1818487243048747008 |
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| author | Osaki Yu Taoka Rikiya Miyauchi Yasuyuki Sugimoto Mikio |
| author_facet | Osaki Yu Taoka Rikiya Miyauchi Yasuyuki Sugimoto Mikio |
| author_sort | Osaki Yu |
| collection | DOAJ |
| description | Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare, rapidly progressive, and often fatal complication of cancer, particularly prostate cancer. A 67-year-old man with advanced prostate cancer developed dyspnea. Chest computed tomography revealed ground-glass opacities across bilateral lung fields, and echocardiography showed right heart failure. As PTTM was suspected, docetaxel chemotherapy was administered immediately. His respiratory condition and right heart failure improved; however, 2-months later his respiratory symptoms were exacerbated, causing death. Autopsy showed fibrocellular intimal proliferation of the small pulmonary arteries, which confirmed PTTM induced by prostate cancer. Although PTTM is fatal, early diagnosis and treatment would improve the prognosis. Keywords: Autopsy, Prostate cancer, Dyspnea, Pulmonary tumor thrombotic microangiopathy, Docetaxel chemotherapy |
| first_indexed | 2024-12-10T16:35:17Z |
| format | Article |
| id | doaj.art-b13b0cfdb37d4693a02955a21bb6957f |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-12-10T16:35:17Z |
| publishDate | 2020-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-b13b0cfdb37d4693a02955a21bb6957f2022-12-22T01:41:26ZengElsevierUrology Case Reports2214-44202020-03-0129Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case reportOsaki Yu0Taoka Rikiya1Miyauchi Yasuyuki2Sugimoto Mikio3Department of Urology, Himeji Medical Center, 68 Honmachi, Himeji-shi, Hyogo-ken, 670-8520, Japan; Corresponding author.Department of Urology, Kagawa University Hospital, 1750-1 Mikicho Ikenobe, Kida-gun, Kagawa-ken, 761-0793, JapanDepartment of Urology, Kagawa University Hospital, 1750-1 Mikicho Ikenobe, Kida-gun, Kagawa-ken, 761-0793, JapanDepartment of Urology, Kagawa University Hospital, 1750-1 Mikicho Ikenobe, Kida-gun, Kagawa-ken, 761-0793, JapanPulmonary tumor thrombotic microangiopathy (PTTM) is a rare, rapidly progressive, and often fatal complication of cancer, particularly prostate cancer. A 67-year-old man with advanced prostate cancer developed dyspnea. Chest computed tomography revealed ground-glass opacities across bilateral lung fields, and echocardiography showed right heart failure. As PTTM was suspected, docetaxel chemotherapy was administered immediately. His respiratory condition and right heart failure improved; however, 2-months later his respiratory symptoms were exacerbated, causing death. Autopsy showed fibrocellular intimal proliferation of the small pulmonary arteries, which confirmed PTTM induced by prostate cancer. Although PTTM is fatal, early diagnosis and treatment would improve the prognosis. Keywords: Autopsy, Prostate cancer, Dyspnea, Pulmonary tumor thrombotic microangiopathy, Docetaxel chemotherapyhttp://www.sciencedirect.com/science/article/pii/S221444201930419X |
| spellingShingle | Osaki Yu Taoka Rikiya Miyauchi Yasuyuki Sugimoto Mikio Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report Urology Case Reports |
| title | Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report |
| title_full | Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report |
| title_fullStr | Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report |
| title_full_unstemmed | Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report |
| title_short | Docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19-9: A case report |
| title_sort | docetaxel chemotherapy temporarily improved pulmonary tumor thrombotic microangiopathy induced by prostate cancer secreting carcinoembryonic antigen and carbohydrate antigen 19 9 a case report |
| url | http://www.sciencedirect.com/science/article/pii/S221444201930419X |
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