Comparative evaluation of bovine porous bone mineral

<b>Background:</b> The aim of the present clinical study was to compare the efficacy of bovine porous bone mineral (BPBM) with and without platelet-rich plasma (PRP) for the treatment of periodontal intrabony defects. <b>Materials and Methods:</b> Twenty eight identical bila...

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Bibliographic Details
Main Authors: Parimala M, Mehta D
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:http://www.jisponline.com/article.asp?issn=0972-124X;year=2010;volume=14;issue=2;spage=126;epage=131;aulast=Parimala
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Summary:<b>Background:</b> The aim of the present clinical study was to compare the efficacy of bovine porous bone mineral (BPBM) with and without platelet-rich plasma (PRP) for the treatment of periodontal intrabony defects. <b>Materials and Methods:</b> Twenty eight identical bilateral periodontal intrabony defects were selected from 14 chronic periodontitis patients. The subjects were randomly assigned to test group (BPBM&#x002B;PRP) or the control group (BPBM). The clinical, radiographic, and intrasurgical (re-entry) measurements were made at baseline and at 9 months postoperatively. <b>Results:</b> Both treatment modalities resulted in significant reduction in probing depth and gain in clinical attachment level as compared to baseline values. The probing depth reduction was 6.20&#177;1.40 mm in BPBM and 6.60&#177;1.43 mm for the BPBM/PRP-treated sites. The gain in clinical attachment level observed was 4.16&#177;1.05 mm for BPBM and 4.70&#177;0.76 mm for the BPBM/PRP group. Radiographically, there was a significant defect fill (3.83&#177;1.01 mm) for the BPBM group and (4.04&#177;1.77 mm) in the BPBM/PRP group. Similar trend was observed between the two groups in relation to intrasurgical parameters. <b>Conclusions:</b> The combination therapy (BPBM&#x002B;PRP) showed more favorable clinical outcome in the treatment of intrabony defects than the BPBM alone group, although the mean difference between the two groups was statistically nonsignificant.
ISSN:0972-124X
0975-1580