Microglia-derived CCL2 has a prime role in neocortex neuroinflammation

Microglia-derived CCL2 has a prime role in neocortex neuroinflammation

Abstract Background In myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE), several areas of demyelination are detectable in mouse cerebral cortex, where neuroinflammation events are associated with scarce inflammatory infiltrates and blood–brain barrier...

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Bibliographic Details
Main Authors: Mariella Errede, Tiziana Annese, Valentina Petrosino, Giovanna Longo, Francesco Girolamo, Ignazio de Trizio, Antonio d’Amati, Antonio Uccelli, Nicole Kerlero de Rosbo, Daniela Virgintino
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Fluids and Barriers of the CNS
Subjects:
Experimental autoimmune encephalomyelitis
Neocortex
Microglia
CCL2
Mesenchymal stem cells
Online Access:https://doi.org/10.1186/s12987-022-00365-5

Internet

https://doi.org/10.1186/s12987-022-00365-5

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