Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation
During their synthesis in the cell nucleus, most eukaryotic mRNAs undergo a two‐step 3′‐end processing reaction in which the pre‐mRNA is cleaved and released from the transcribing RNA polymerase II and a polyadenosine (poly(A)) tail is added to the newly formed 3′‐end. These biochemical reactions mi...
Main Authors: | Juan B. Rodríguez‐Molina, Matti Turtola |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2023-07-01
|
Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.13528 |
Similar Items
-
mRNA alternative polyadenylation (APA) in regulation of gene expression and diseases
by: Siyao Guo, et al.
Published: (2023-01-01) -
CPSF30 at the Interface of Alternative Polyadenylation and Cellular Signaling in Plants
by: Manohar Chakrabarti, et al.
Published: (2015-06-01) -
Nucleotide-level linkage of transcriptional elongation and polyadenylation
by: Joseph V Geisberg, et al.
Published: (2022-11-01) -
Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders
by: Jamie Nourse, et al.
Published: (2020-06-01) -
PARN-like Proteins Regulate Gene Expression in Land Plant Mitochondria by Modulating mRNA Polyadenylation
by: Takashi Hirayama
Published: (2021-10-01)