Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition
The effects of a protein-restricted diet (8% protein, 81% carbohydrate and 11% lipids) on Schistosoma mansoni infectivity, fecal egg excretion and intestinal egg distribution in Swiss (SW) mice were studied. Pregnant mice received a deficient diet from the middle of gestation until delivery. Seven-d...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2002-10-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000900027 |
| _version_ | 1797721515029954560 |
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| author | Carla Simões Renata Heisler Neves Lucas de Andrade Barros Patrícia Dias Brito Cristiane Oliveira Cravo Egberto Gaspar de Moura José Roberto Machado-Silva |
| author_facet | Carla Simões Renata Heisler Neves Lucas de Andrade Barros Patrícia Dias Brito Cristiane Oliveira Cravo Egberto Gaspar de Moura José Roberto Machado-Silva |
| author_sort | Carla Simões |
| collection | DOAJ |
| description | The effects of a protein-restricted diet (8% protein, 81% carbohydrate and 11% lipids) on Schistosoma mansoni infectivity, fecal egg excretion and intestinal egg distribution in Swiss (SW) mice were studied. Pregnant mice received a deficient diet from the middle of gestation until delivery. Seven-days-old mice were exposed to 50 cercariae (BH strain, Brazil). Offspring mice had a free access to the deficient diet since lactation until adulthood. The controls were fed with a commercial mice diet. A parasitological examination was performed between six and eight weeks post-infection while both groups were necropsied one week later. Mice on the experimental diet showed a significant loss in body weight. There was no significant difference (p > 0.05) in pre-patent period, kinetics of egg excretion and worm recovery from mice on either diet. Significant differences (p < 0.05) were found concerning to the percentage of deposited eggs in the distal segment of the small intestine from hosts on the experimental diet.Our data suggest that experimental malnutrition induced for a long term has no detrimental effect on the acute schistosomiais infection in SW mice. |
| first_indexed | 2024-03-12T09:34:25Z |
| format | Article |
| id | doaj.art-b14d6415b7ee40e5aac5c16399874752 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T09:34:25Z |
| publishDate | 2002-10-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-b14d6415b7ee40e5aac5c163998747522023-09-02T13:48:57ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602002-10-019714314710.1590/S0074-02762002000900027Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutritionCarla SimõesRenata Heisler NevesLucas de Andrade BarrosPatrícia Dias BritoCristiane Oliveira CravoEgberto Gaspar de MouraJosé Roberto Machado-SilvaThe effects of a protein-restricted diet (8% protein, 81% carbohydrate and 11% lipids) on Schistosoma mansoni infectivity, fecal egg excretion and intestinal egg distribution in Swiss (SW) mice were studied. Pregnant mice received a deficient diet from the middle of gestation until delivery. Seven-days-old mice were exposed to 50 cercariae (BH strain, Brazil). Offspring mice had a free access to the deficient diet since lactation until adulthood. The controls were fed with a commercial mice diet. A parasitological examination was performed between six and eight weeks post-infection while both groups were necropsied one week later. Mice on the experimental diet showed a significant loss in body weight. There was no significant difference (p > 0.05) in pre-patent period, kinetics of egg excretion and worm recovery from mice on either diet. Significant differences (p < 0.05) were found concerning to the percentage of deposited eggs in the distal segment of the small intestine from hosts on the experimental diet.Our data suggest that experimental malnutrition induced for a long term has no detrimental effect on the acute schistosomiais infection in SW mice.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000900027Schistosoma mansonibiological studymalnutritionlactationSwiss mice |
| spellingShingle | Carla Simões Renata Heisler Neves Lucas de Andrade Barros Patrícia Dias Brito Cristiane Oliveira Cravo Egberto Gaspar de Moura José Roberto Machado-Silva Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition Memorias do Instituto Oswaldo Cruz Schistosoma mansoni biological study malnutrition lactation Swiss mice |
| title | Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition |
| title_full | Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition |
| title_fullStr | Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition |
| title_full_unstemmed | Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition |
| title_short | Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition |
| title_sort | parasitological characteristics of schistosoma mansoni infection in swiss mice with underlying malnutrition |
| topic | Schistosoma mansoni biological study malnutrition lactation Swiss mice |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000900027 |
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