Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α
Summary: Remyelination is a multistep regenerative process that results in the reformation of myelin sheaths around demyelinated axons and is a critical therapeutic target. Here we show that immediate access to a running wheel following toxin-induced demyelination in mice enhances oligodendrogenesis...
Main Authors: | Samuel K. Jensen, Nathan J. Michaels, Slava Ilyntskyy, Michael B. Keough, Olga Kovalchuk, V. Wee Yong |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718313470 |
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