Cellular prion protein protects from inflammatory and neuropathic pain

Cellular prion protein protects from inflammatory and neuropathic pain

<p>Abstract</p> <p>Cellular prion protein (PrP<sup>C</sup>) inhibits <it>N</it>-Methyl-<it>D</it>-Aspartate (NMDA) receptors. Since NMDA receptors play an important role in the transmission of pain signals in the dorsal horn of spinal cord, we th...

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Bibliographic Details
Main Authors: Zamponi Gerald W, Gadotti Vinicius M
Format: Article
Language:English
Published: SAGE Publishing 2011-08-01
Series:Molecular Pain
Subjects:
Prion protein
pain
knockout mice
NMDA receptor
spinal cord
Online Access:http://www.molecularpain.com/content/7/1/59

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