Down-regulated NEDD4L facilitates tumor progression through activating Notch signaling in lung adenocarcinoma

Down-regulated NEDD4L facilitates tumor progression through activating Notch signaling in lung adenocarcinoma

Neural precursor cell expressed developmentally down-regulated 4-like protein (NEDD4L), an E3 ubiquitin ligase, exerts an important role in diverse biological processes including development, tumorigenesis, and tumor progression. Although the role of NEDD4L in the pathogenesis of lung adenocarcinoma...

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Bibliographic Details
Main Authors: Liping Lin, Xuan Wu, Yuanxue Jiang, Caijiu Deng, Xi Luo, Jianjun Han, Jiazhu Hu, Xiaolong Cao
Format: Article
Language:English
Published: PeerJ Inc. 2022-05-01
Series:PeerJ
Subjects:
Lung adenocarcinoma
NEDD4L
Notch2
Hes1
RO4929097
Online Access:https://peerj.com/articles/13402.pdf

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