Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes
Magnetic resonance imaging (MRI) has the potential to improve our understanding of diabetes and improve both diagnosis and monitoring of the disease. Although the spatial resolution of MRI is insufficient to directly image the endocrine pancreas in people, the increasing awareness that the exocrine...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2020.592349/full |
| _version_ | 1818854778998882304 |
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| author | John Virostko John Virostko John Virostko |
| author_facet | John Virostko John Virostko John Virostko |
| author_sort | John Virostko |
| collection | DOAJ |
| description | Magnetic resonance imaging (MRI) has the potential to improve our understanding of diabetes and improve both diagnosis and monitoring of the disease. Although the spatial resolution of MRI is insufficient to directly image the endocrine pancreas in people, the increasing awareness that the exocrine pancreas is also involved in diabetes pathogenesis has spurred new MRI applications. These techniques build upon studies of exocrine pancreatic diseases, for which MRI has already developed into a routine clinical tool for diagnosis and monitoring of pancreatic cancer and pancreatitis. By adjusting the imaging contrast and carefully controlling image acquisition and processing, MRI can quantify a variety of tissue pathologies. This review introduces a number of quantitative MRI techniques that have been applied to study the diabetic pancreas, summarizes progress in validating and standardizing each technique, and discusses the need for image analyses that account for spatial heterogeneity in the pancreas. |
| first_indexed | 2024-12-19T07:58:07Z |
| format | Article |
| id | doaj.art-b15f056f56f4499cac972a783861451a |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-12-19T07:58:07Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-b15f056f56f4499cac972a783861451a2022-12-21T20:29:57ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922020-12-011110.3389/fendo.2020.592349592349Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With DiabetesJohn Virostko0John Virostko1John Virostko2Department of Diagnostic Medicine, University of Texas at Austin, Austin, TX, United StatesLivestrong Cancer Institutes, University of Texas at Austin, Austin, TX, United StatesDepartment of Oncology, University of Texas at Austin, Austin, TX, United StatesMagnetic resonance imaging (MRI) has the potential to improve our understanding of diabetes and improve both diagnosis and monitoring of the disease. Although the spatial resolution of MRI is insufficient to directly image the endocrine pancreas in people, the increasing awareness that the exocrine pancreas is also involved in diabetes pathogenesis has spurred new MRI applications. These techniques build upon studies of exocrine pancreatic diseases, for which MRI has already developed into a routine clinical tool for diagnosis and monitoring of pancreatic cancer and pancreatitis. By adjusting the imaging contrast and carefully controlling image acquisition and processing, MRI can quantify a variety of tissue pathologies. This review introduces a number of quantitative MRI techniques that have been applied to study the diabetic pancreas, summarizes progress in validating and standardizing each technique, and discusses the need for image analyses that account for spatial heterogeneity in the pancreas.https://www.frontiersin.org/articles/10.3389/fendo.2020.592349/fullMRIvolumerelaxometryperfusiontype 2 diabetestype 1 diabetes |
| spellingShingle | John Virostko John Virostko John Virostko Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes Frontiers in Endocrinology MRI volume relaxometry perfusion type 2 diabetes type 1 diabetes |
| title | Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes |
| title_full | Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes |
| title_fullStr | Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes |
| title_full_unstemmed | Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes |
| title_short | Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes |
| title_sort | quantitative magnetic resonance imaging of the pancreas of individuals with diabetes |
| topic | MRI volume relaxometry perfusion type 2 diabetes type 1 diabetes |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2020.592349/full |
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