Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease
Background/Aims Sacroiliitis is a frequent extraintestinal manifestation of inflammatory bowel diseases (IBDs). This study aimed to assess the prevalence of sacroiliitis using a validated screening tool based on abdominopelvic computed tomography (APCT) in Korean patients with Crohn’s disease (CD) a...
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| Format: | Article |
| Language: | English |
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The Korean Association of Internal Medicine
2021-07-01
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| Series: | The Korean Journal of Internal Medicine |
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| Online Access: | http://www.kjim.org/upload/pdf/kjim-2020-199.pdf |
| _version_ | 1818456545927626752 |
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| author | You-Jung Ha Hyo Jin Kim Eugene Lee Ji Hye Park Young Soo Park Yun Jong Lee Yusuhn Kang Hyuk Yoon |
| author_facet | You-Jung Ha Hyo Jin Kim Eugene Lee Ji Hye Park Young Soo Park Yun Jong Lee Yusuhn Kang Hyuk Yoon |
| author_sort | You-Jung Ha |
| collection | DOAJ |
| description | Background/Aims Sacroiliitis is a frequent extraintestinal manifestation of inflammatory bowel diseases (IBDs). This study aimed to assess the prevalence of sacroiliitis using a validated screening tool based on abdominopelvic computed tomography (APCT) in Korean patients with Crohn’s disease (CD) and examine potential associations between clinical characteristics and sacroiliitis. Methods One hundred five patients with CD undergoing APCT for any indication at an IBD clinic were matched 1:1 for age and sex with 105 controls without underlying chronic illnesses. Using a validated APCT screening tool that defines sacroiliitis as either ankylosis or a total erosion score (TES) ≥ 3, all computed tomography scans were assessed by two independent, blinded radiologists. We compared the prevalence of sacroiliitis between CD patients and controls and clinical characteristics between CD patients with and without sacroiliitis. Results The prevalence of sacroiliitis was significantly higher in CD patients than in controls (13.3% vs. 4.8%, p = 0.030). All subjects with sacroiliitis had a TES ≥ 3, but no ankylosis. The assessment of sacroiliitis in APCT showed excellent interreader reliability (Cohen’s kappa = 0.933 for presence of sacroiliitis). Sacroiliitis in CD patients was bilateral and asymptomatic. There were no significant associations between sacroiliitis and any demographic data or clinical characteristics in these patients. Conclusions The prevalence of APCT-detected sacroiliitis in CD patients was higher than that in controls, but the condition was asymptomatic. The clinical significance of asymptomatic sacroiliitis in Korean CD patients remains unclear. |
| first_indexed | 2024-12-14T22:28:23Z |
| format | Article |
| id | doaj.art-b15f0a6a464141b28598e24d9f9e97f2 |
| institution | Directory Open Access Journal |
| issn | 1226-3303 2005-6648 |
| language | English |
| last_indexed | 2024-12-14T22:28:23Z |
| publishDate | 2021-07-01 |
| publisher | The Korean Association of Internal Medicine |
| record_format | Article |
| series | The Korean Journal of Internal Medicine |
| spelling | doaj.art-b15f0a6a464141b28598e24d9f9e97f22022-12-21T22:45:18ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482021-07-0136486887710.3904/kjim.2020.199170428Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s diseaseYou-Jung Ha0Hyo Jin Kim1Eugene Lee2Ji Hye Park3Young Soo Park4Yun Jong Lee5Yusuhn Kang6Hyuk Yoon7 Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea Department of Radiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaBackground/Aims Sacroiliitis is a frequent extraintestinal manifestation of inflammatory bowel diseases (IBDs). This study aimed to assess the prevalence of sacroiliitis using a validated screening tool based on abdominopelvic computed tomography (APCT) in Korean patients with Crohn’s disease (CD) and examine potential associations between clinical characteristics and sacroiliitis. Methods One hundred five patients with CD undergoing APCT for any indication at an IBD clinic were matched 1:1 for age and sex with 105 controls without underlying chronic illnesses. Using a validated APCT screening tool that defines sacroiliitis as either ankylosis or a total erosion score (TES) ≥ 3, all computed tomography scans were assessed by two independent, blinded radiologists. We compared the prevalence of sacroiliitis between CD patients and controls and clinical characteristics between CD patients with and without sacroiliitis. Results The prevalence of sacroiliitis was significantly higher in CD patients than in controls (13.3% vs. 4.8%, p = 0.030). All subjects with sacroiliitis had a TES ≥ 3, but no ankylosis. The assessment of sacroiliitis in APCT showed excellent interreader reliability (Cohen’s kappa = 0.933 for presence of sacroiliitis). Sacroiliitis in CD patients was bilateral and asymptomatic. There were no significant associations between sacroiliitis and any demographic data or clinical characteristics in these patients. Conclusions The prevalence of APCT-detected sacroiliitis in CD patients was higher than that in controls, but the condition was asymptomatic. The clinical significance of asymptomatic sacroiliitis in Korean CD patients remains unclear.http://www.kjim.org/upload/pdf/kjim-2020-199.pdfsacroiliitissacroiliac jointtomographyspiral computedcrohn disease |
| spellingShingle | You-Jung Ha Hyo Jin Kim Eugene Lee Ji Hye Park Young Soo Park Yun Jong Lee Yusuhn Kang Hyuk Yoon Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease The Korean Journal of Internal Medicine sacroiliitis sacroiliac joint tomography spiral computed crohn disease |
| title | Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease |
| title_full | Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease |
| title_fullStr | Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease |
| title_full_unstemmed | Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease |
| title_short | Subclinical sacroiliitis detected by abdominopelvic computed tomography in Korean patients with Crohn’s disease |
| title_sort | subclinical sacroiliitis detected by abdominopelvic computed tomography in korean patients with crohn s disease |
| topic | sacroiliitis sacroiliac joint tomography spiral computed crohn disease |
| url | http://www.kjim.org/upload/pdf/kjim-2020-199.pdf |
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