Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis
Abstract Objectives To identify age-related radiographic risk factors for degenerative lumbar spinal stenosis (DLSS) and analyze correlations among them. Methods A total of 180 cases were enrolled in this study, and lumbar magnetic resonance was performed. Among them, 93 cases suffered DLSS and lumb...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-022-03374-0 |
| _version_ | 1797984631441588224 |
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| author | Donglai Li Lianlei Wang Zheng Wang Chao Li Suomao Yuan Yonghao Tian Xuguang Yu Xinyu Liu |
| author_facet | Donglai Li Lianlei Wang Zheng Wang Chao Li Suomao Yuan Yonghao Tian Xuguang Yu Xinyu Liu |
| author_sort | Donglai Li |
| collection | DOAJ |
| description | Abstract Objectives To identify age-related radiographic risk factors for degenerative lumbar spinal stenosis (DLSS) and analyze correlations among them. Methods A total of 180 cases were enrolled in this study, and lumbar magnetic resonance was performed. Among them, 93 cases suffered DLSS and lumbar dynamic X-ray was examined. And following parameters were measured and evaluated: intervertebral disk height (IDH), the ratio of IDH(IDHL4-5/L3-4), initial IDH of L4-5(iIDHL4-5) in the DLSS group, disk degeneration (DD), cartilaginous endplate failure (CEF), Modic changes, the thickness of ligamentum flavum (LF), range of intervertebral motion (ROM), facet joint opening (FJO), facet joint angle (FJA), the standard cross-sectional area (SCSA) of the multifidus, erector spinae, and psoas major muscles. The data of two groups were compared, and the possible risk factors of DLSS were analyzed. Results Compared with the control group, the DLSS group had higher IDH except for L4-5 and larger iIDHL4-5 (P < 0.05). Significant differences were shown in CEF and the thickness of LF at L1-S1 and DD at L4-5 (P < 0.05). The DLSS group had smaller SCSA of multifidus, erector spinae, and psoas major muscles but greater FJA, FJO (P < 0.05). And the risk of DLSS increased when iIDHL4-5 ≥ 10.73 mm, FJA ≥ 52.03° , or FJO ≥ 3.75 mm. IDH positively correlated with SCSA of multifidus and psoas major muscles and ROM at L1-S1 (P < 0.05). DD showed negative linear relations with SCSA of multifidus and psoas muscle and positive linear relation with CEF at L1-2, L2-3, and L5-S1 (P < 0.05). Conclusion Larger initial disk height and excessive CEF may induce DLSS by increasing intervertebral mobility to promote DD, and atrophied paravertebral muscles by weakening the stability of lumbar spine. |
| first_indexed | 2024-04-11T07:04:44Z |
| format | Article |
| id | doaj.art-b15f436f73104cbc8c6431657cffdc1d |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-11T07:04:44Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-b15f436f73104cbc8c6431657cffdc1d2022-12-22T04:38:25ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2022-11-0117111010.1186/s13018-022-03374-0Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysisDonglai Li0Lianlei Wang1Zheng Wang2Chao Li3Suomao Yuan4Yonghao Tian5Xuguang Yu6Xinyu Liu7Department of Orthopedics, Qilu Hospital of Shandong UniversityDepartment of Orthopedics, Qilu Hospital of Shandong UniversityDepartment of Orthopedics, Qilu Hospital of Shandong UniversityDepartment of Orthopedics, Qilu Hospital of Shandong UniversityDepartment of Orthopedics, Qilu Hospital of Shandong UniversityDepartment of Orthopedics, Qilu Hospital of Shandong UniversitySchool of Physical Education, Shandong UniversityDepartment of Orthopedics, Qilu Hospital of Shandong UniversityAbstract Objectives To identify age-related radiographic risk factors for degenerative lumbar spinal stenosis (DLSS) and analyze correlations among them. Methods A total of 180 cases were enrolled in this study, and lumbar magnetic resonance was performed. Among them, 93 cases suffered DLSS and lumbar dynamic X-ray was examined. And following parameters were measured and evaluated: intervertebral disk height (IDH), the ratio of IDH(IDHL4-5/L3-4), initial IDH of L4-5(iIDHL4-5) in the DLSS group, disk degeneration (DD), cartilaginous endplate failure (CEF), Modic changes, the thickness of ligamentum flavum (LF), range of intervertebral motion (ROM), facet joint opening (FJO), facet joint angle (FJA), the standard cross-sectional area (SCSA) of the multifidus, erector spinae, and psoas major muscles. The data of two groups were compared, and the possible risk factors of DLSS were analyzed. Results Compared with the control group, the DLSS group had higher IDH except for L4-5 and larger iIDHL4-5 (P < 0.05). Significant differences were shown in CEF and the thickness of LF at L1-S1 and DD at L4-5 (P < 0.05). The DLSS group had smaller SCSA of multifidus, erector spinae, and psoas major muscles but greater FJA, FJO (P < 0.05). And the risk of DLSS increased when iIDHL4-5 ≥ 10.73 mm, FJA ≥ 52.03° , or FJO ≥ 3.75 mm. IDH positively correlated with SCSA of multifidus and psoas major muscles and ROM at L1-S1 (P < 0.05). DD showed negative linear relations with SCSA of multifidus and psoas muscle and positive linear relation with CEF at L1-2, L2-3, and L5-S1 (P < 0.05). Conclusion Larger initial disk height and excessive CEF may induce DLSS by increasing intervertebral mobility to promote DD, and atrophied paravertebral muscles by weakening the stability of lumbar spine.https://doi.org/10.1186/s13018-022-03374-0Degenerative lumbar spinal stenosisIntervertebral disk heightCartilaginous endplate failureIntervertebral disk degenerationLigamentum flavum |
| spellingShingle | Donglai Li Lianlei Wang Zheng Wang Chao Li Suomao Yuan Yonghao Tian Xuguang Yu Xinyu Liu Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis Journal of Orthopaedic Surgery and Research Degenerative lumbar spinal stenosis Intervertebral disk height Cartilaginous endplate failure Intervertebral disk degeneration Ligamentum flavum |
| title | Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis |
| title_full | Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis |
| title_fullStr | Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis |
| title_full_unstemmed | Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis |
| title_short | Age-related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis |
| title_sort | age related radiographic parameters difference between the degenerative lumbar spinal stenosis patients and healthy people and correlation analysis |
| topic | Degenerative lumbar spinal stenosis Intervertebral disk height Cartilaginous endplate failure Intervertebral disk degeneration Ligamentum flavum |
| url | https://doi.org/10.1186/s13018-022-03374-0 |
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