Topical therapy of dermatoses in children with complex localizations
The skin of children has its own anatomical and physiological characteristics, the epidermis is much thinner than in adults, the layers of the dermis and basement membrane are poorly developed and differentiated, the rate of transepidermal water loss is increased and the level of natural moisturizin...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2021-11-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/6501 |
| _version_ | 1827962510066581504 |
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| author | J. S. Kovaleva M. V. Orobei N. K. Zyablitskaya N. K. Bishevskaya |
| author_facet | J. S. Kovaleva M. V. Orobei N. K. Zyablitskaya N. K. Bishevskaya |
| author_sort | J. S. Kovaleva |
| collection | DOAJ |
| description | The skin of children has its own anatomical and physiological characteristics, the epidermis is much thinner than in adults, the layers of the dermis and basement membrane are poorly developed and differentiated, the rate of transepidermal water loss is increased and the level of natural moisturizing factor (NMF) is reduced. Such a structure of the skin predisposes to a violation of its barrier function, contributes to the occurrence of skin diseases, provides an increased resorptive capacity of the skin and requires special attention when prescribing external therapy. The use of high-quality emollients is an important part of the basic treatment of chronic dermatoses and has its own characteristics in childhood. The use of emollients prevents the development of exacerbations and reduces the need for anti-inflammatory topical drugs. With the localization of the inflammatory process on the face, neck, genitals and large folds, it is necessary to give preference to short courses of topical glucocorticosteroids (THCS) with sufficient anti-inflammatory activity, rapid onset of action, minimal side effects. Given the high risk of side effects in children in these areas of the skin, strong fluorinated THCS, high-potency THCS, and the use of THCS under occlusive dressings are not recommended. The Russian experience of using 0.1% methylprednisolone aceponate in children of various age groups in the treatment of allergic dermatoses, including those with localization in sensitive areas, has shown good efficacy, tolerance and the absence of side effects. he article presents own clinical observations of the effectiveness of the use of combination therapy: an emollient agent - a special cream with physiological lipids omega 3-6-9 and cream methylprednisolone aceponate (with ceramides in the base) in the treatment of skin diseases in children with an emphasis on complex localizations, such as face, folds, genital area. |
| first_indexed | 2024-04-09T16:43:46Z |
| format | Article |
| id | doaj.art-b16411cef1da41779d9464a0bd09022f |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:43:46Z |
| publishDate | 2021-11-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-b16411cef1da41779d9464a0bd09022f2023-04-23T06:56:35ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902021-11-0101719220210.21518/2079-701X-2021-17-192-2025871Topical therapy of dermatoses in children with complex localizationsJ. S. Kovaleva0M. V. Orobei1N. K. Zyablitskaya2N. K. Bishevskaya3Altay State Medical UniversityAltay State Medical UniversityAltay State Medical UniversityAltay State Medical UniversityThe skin of children has its own anatomical and physiological characteristics, the epidermis is much thinner than in adults, the layers of the dermis and basement membrane are poorly developed and differentiated, the rate of transepidermal water loss is increased and the level of natural moisturizing factor (NMF) is reduced. Such a structure of the skin predisposes to a violation of its barrier function, contributes to the occurrence of skin diseases, provides an increased resorptive capacity of the skin and requires special attention when prescribing external therapy. The use of high-quality emollients is an important part of the basic treatment of chronic dermatoses and has its own characteristics in childhood. The use of emollients prevents the development of exacerbations and reduces the need for anti-inflammatory topical drugs. With the localization of the inflammatory process on the face, neck, genitals and large folds, it is necessary to give preference to short courses of topical glucocorticosteroids (THCS) with sufficient anti-inflammatory activity, rapid onset of action, minimal side effects. Given the high risk of side effects in children in these areas of the skin, strong fluorinated THCS, high-potency THCS, and the use of THCS under occlusive dressings are not recommended. The Russian experience of using 0.1% methylprednisolone aceponate in children of various age groups in the treatment of allergic dermatoses, including those with localization in sensitive areas, has shown good efficacy, tolerance and the absence of side effects. he article presents own clinical observations of the effectiveness of the use of combination therapy: an emollient agent - a special cream with physiological lipids omega 3-6-9 and cream methylprednisolone aceponate (with ceramides in the base) in the treatment of skin diseases in children with an emphasis on complex localizations, such as face, folds, genital area.https://www.med-sovet.pro/jour/article/view/6501features of children’s skinsensitive skin areastopical glucocorticosteroidsemollientssteroid-sensitive dermatoses |
| spellingShingle | J. S. Kovaleva M. V. Orobei N. K. Zyablitskaya N. K. Bishevskaya Topical therapy of dermatoses in children with complex localizations Медицинский совет features of children’s skin sensitive skin areas topical glucocorticosteroids emollients steroid-sensitive dermatoses |
| title | Topical therapy of dermatoses in children with complex localizations |
| title_full | Topical therapy of dermatoses in children with complex localizations |
| title_fullStr | Topical therapy of dermatoses in children with complex localizations |
| title_full_unstemmed | Topical therapy of dermatoses in children with complex localizations |
| title_short | Topical therapy of dermatoses in children with complex localizations |
| title_sort | topical therapy of dermatoses in children with complex localizations |
| topic | features of children’s skin sensitive skin areas topical glucocorticosteroids emollients steroid-sensitive dermatoses |
| url | https://www.med-sovet.pro/jour/article/view/6501 |
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