Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders

Introduction: Chemosensory disorders have been identified as typical symptoms of COVID-19. Objective: To characterize patients with COVID-19 and referred chemosensory disorders. Methods: 152 hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical an...

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Main Authors: Sergio César Lorenzo González, Elizabeth Proenza Ramírez, José Adrián Romero García, Yosvanis Leyva Zamora, Alexánder Fernández Zaldívar
Format: Article
Language:Spanish
Published: ECIMED 2021-11-01
Series:Revista Cubana de Medicina Militar
Subjects:
Online Access:http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1526
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author Sergio César Lorenzo González
Elizabeth Proenza Ramírez
José Adrián Romero García
Yosvanis Leyva Zamora
Alexánder Fernández Zaldívar
author_facet Sergio César Lorenzo González
Elizabeth Proenza Ramírez
José Adrián Romero García
Yosvanis Leyva Zamora
Alexánder Fernández Zaldívar
author_sort Sergio César Lorenzo González
collection DOAJ
description Introduction: Chemosensory disorders have been identified as typical symptoms of COVID-19. Objective: To characterize patients with COVID-19 and referred chemosensory disorders. Methods: 152 hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical and epidemiological variables, inflammation markers, chest X-ray and treatment used were studied. Results: The average age was 40.2 years, the female sex 59.2% and the antecedent prevailed, confirmed case contact (62.5%), with anosmia (95.7%), ageusia (93.3%), without comorbidities (53.3%) and absence of accompanying symptoms (36.8%). In patients with an indeterminate source of infection, confirmation was late (3.89 days); there were no significant differences between those who presented one or both disorders (p = 0.053), nor between those who did or did not present associated symptoms (p = 0.14). In 2% the neutrophil index was greater than 4; 3.3% had an absolute lymphocyte count lower than 1500x106/L and 68.4% did not show radiological alteration. 5.9% required antimicrobials and 5.3% immunomodulators; 1.3% were admitted to intensive care. Most (95.4%) were discharged from the clinic and 1.3% died. Conclusions: The female sex predominates, with ageusia or anosmia; those who do not have an epidemiological history are diagnosed with delay. There are no differences in seeking care, for one or both disorders, or for accompanying symptoms. They refer more in the absence of complications and serious pictures. Those who refer them spontaneously are generally healthy and oligosymptomatic people.
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spelling doaj.art-b16420f126724370b2cd00f7f863cab82022-12-21T22:42:22ZspaECIMEDRevista Cubana de Medicina Militar1561-30462021-11-01504e02101526e02101526482Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disordersSergio César Lorenzo González0Elizabeth Proenza Ramírez1José Adrián Romero García2Yosvanis Leyva Zamora3Alexánder Fernández Zaldívar4Hospital Militar Dr Fermín Valdés DomínguezHospital Clínico Quirúrgico Lucía Íñiguez LandínHospital Militar Dr Fermín Valdés Domínguez.Hospital Militar Dr Fermín Valdés DomínguezHospital Militar Dr Fermín Valdés Domínguez.Introduction: Chemosensory disorders have been identified as typical symptoms of COVID-19. Objective: To characterize patients with COVID-19 and referred chemosensory disorders. Methods: 152 hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical and epidemiological variables, inflammation markers, chest X-ray and treatment used were studied. Results: The average age was 40.2 years, the female sex 59.2% and the antecedent prevailed, confirmed case contact (62.5%), with anosmia (95.7%), ageusia (93.3%), without comorbidities (53.3%) and absence of accompanying symptoms (36.8%). In patients with an indeterminate source of infection, confirmation was late (3.89 days); there were no significant differences between those who presented one or both disorders (p = 0.053), nor between those who did or did not present associated symptoms (p = 0.14). In 2% the neutrophil index was greater than 4; 3.3% had an absolute lymphocyte count lower than 1500x106/L and 68.4% did not show radiological alteration. 5.9% required antimicrobials and 5.3% immunomodulators; 1.3% were admitted to intensive care. Most (95.4%) were discharged from the clinic and 1.3% died. Conclusions: The female sex predominates, with ageusia or anosmia; those who do not have an epidemiological history are diagnosed with delay. There are no differences in seeking care, for one or both disorders, or for accompanying symptoms. They refer more in the absence of complications and serious pictures. Those who refer them spontaneously are generally healthy and oligosymptomatic people.http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1526covid-19sars-cov-2trastornos del olfatotrastornos del gustoanosmiaageusia.
spellingShingle Sergio César Lorenzo González
Elizabeth Proenza Ramírez
José Adrián Romero García
Yosvanis Leyva Zamora
Alexánder Fernández Zaldívar
Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
Revista Cubana de Medicina Militar
covid-19
sars-cov-2
trastornos del olfato
trastornos del gusto
anosmia
ageusia.
title Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_full Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_fullStr Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_full_unstemmed Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_short Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders
title_sort clinical and epidemiological characteristics of covid 19 patients with chemosensory disorders
topic covid-19
sars-cov-2
trastornos del olfato
trastornos del gusto
anosmia
ageusia.
url http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1526
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