Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma
Background Although histological diagnosis of pilomatricoma is not difficult because of its unique histological features, cytological diagnosis through fine-needle aspiration cytology (FNAC) is often problematic due to misdiagnoses as malignancy. Methods We reviewed the cytological features of 14 ca...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Pathologists & the Korean Society for Cytopathology
2018-01-01
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| Series: | Journal of Pathology and Translational Medicine |
| Subjects: | |
| Online Access: | http://www.jpatholtm.org/upload/pdf/jptm-2017-10-18.pdf |
| _version_ | 1819073029381029888 |
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| author | Kanghee Han Hwa-Jeong Ha Joon Seog Kong Jae Kyung Myung Sunhoo Park Jung-Soon Kim Myung-Soon Shin Hye Sil Seol Jae Soo Koh Seung-Sook Lee |
| author_facet | Kanghee Han Hwa-Jeong Ha Joon Seog Kong Jae Kyung Myung Sunhoo Park Jung-Soon Kim Myung-Soon Shin Hye Sil Seol Jae Soo Koh Seung-Sook Lee |
| author_sort | Kanghee Han |
| collection | DOAJ |
| description | Background Although histological diagnosis of pilomatricoma is not difficult because of its unique histological features, cytological diagnosis through fine-needle aspiration cytology (FNAC) is often problematic due to misdiagnoses as malignancy. Methods We reviewed the cytological features of 14 cases of histologically-proven pilomatricoma from Korea Cancer Center Hospital, with a discussion on the diagnostic pitfalls of FNAC. Results Among 14 cases of pilomatricoma, 10 (71.4%) were correctly diagnosed through FNAC, and two (14.3%) were misdiagnosed as carcinoma. Cytologically, all cases had easily recognizable clusters of basaloid cells and foreign body-type multinucleated cells. Although ghost cells were also found in all cases, some were inconspicuous and hardly recognizable due to their small numbers. Conclusions An accurate diagnosis of pilomatricoma in FNAC is feasible with consideration of clinical information and close examination of ghost cells. |
| first_indexed | 2024-12-21T17:47:07Z |
| format | Article |
| id | doaj.art-b166284711fc45c7b8bff92296f253c0 |
| institution | Directory Open Access Journal |
| issn | 2383-7837 2383-7845 |
| language | English |
| last_indexed | 2024-12-21T17:47:07Z |
| publishDate | 2018-01-01 |
| publisher | Korean Society of Pathologists & the Korean Society for Cytopathology |
| record_format | Article |
| series | Journal of Pathology and Translational Medicine |
| spelling | doaj.art-b166284711fc45c7b8bff92296f253c02022-12-21T18:55:28ZengKorean Society of Pathologists & the Korean Society for CytopathologyJournal of Pathology and Translational Medicine2383-78372383-78452018-01-01521455010.4132/jptm.2017.10.1816749Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of PilomatricomaKanghee HanHwa-Jeong HaJoon Seog KongJae Kyung Myung0Sunhoo ParkJung-Soon KimMyung-Soon ShinHye Sil SeolJae Soo KohSeung-Sook Lee1 Laboratory of Radiation Pathology, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea Laboratory of Radiation Pathology, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, KoreaBackground Although histological diagnosis of pilomatricoma is not difficult because of its unique histological features, cytological diagnosis through fine-needle aspiration cytology (FNAC) is often problematic due to misdiagnoses as malignancy. Methods We reviewed the cytological features of 14 cases of histologically-proven pilomatricoma from Korea Cancer Center Hospital, with a discussion on the diagnostic pitfalls of FNAC. Results Among 14 cases of pilomatricoma, 10 (71.4%) were correctly diagnosed through FNAC, and two (14.3%) were misdiagnosed as carcinoma. Cytologically, all cases had easily recognizable clusters of basaloid cells and foreign body-type multinucleated cells. Although ghost cells were also found in all cases, some were inconspicuous and hardly recognizable due to their small numbers. Conclusions An accurate diagnosis of pilomatricoma in FNAC is feasible with consideration of clinical information and close examination of ghost cells.http://www.jpatholtm.org/upload/pdf/jptm-2017-10-18.pdfPilomatricomaFine-needle aspiration cytologyGhost cells |
| spellingShingle | Kanghee Han Hwa-Jeong Ha Joon Seog Kong Jae Kyung Myung Sunhoo Park Jung-Soon Kim Myung-Soon Shin Hye Sil Seol Jae Soo Koh Seung-Sook Lee Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma Journal of Pathology and Translational Medicine Pilomatricoma Fine-needle aspiration cytology Ghost cells |
| title | Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma |
| title_full | Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma |
| title_fullStr | Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma |
| title_full_unstemmed | Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma |
| title_short | Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma |
| title_sort | importance of individual ghost cells in fine needle aspiration cytology diagnosis of pilomatricoma |
| topic | Pilomatricoma Fine-needle aspiration cytology Ghost cells |
| url | http://www.jpatholtm.org/upload/pdf/jptm-2017-10-18.pdf |
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