In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens
Calluna vulgaris L. Hull (Ericaceae) has been used for treatment of urinary tract infections in traditional medicine. In this study we analyzed in vitro antibacterial activity of the plant extracts on different strains of Escherichia coli, Enterococcus faecalis and Proteus vulgaris, as well as the...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2014-11-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/40 |
| _version_ | 1827317398570532864 |
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| author | Dragana M Vučić Miroslav R Petković Branka B Rodić-Grabovac Olgica D Stefanović Sava M Vasić Ljiljana R Čomić |
| author_facet | Dragana M Vučić Miroslav R Petković Branka B Rodić-Grabovac Olgica D Stefanović Sava M Vasić Ljiljana R Čomić |
| author_sort | Dragana M Vučić |
| collection | DOAJ |
| description |
Calluna vulgaris L. Hull (Ericaceae) has been used for treatment of urinary tract infections in traditional medicine. In this study we analyzed in vitro antibacterial activity of the plant extracts on different strains of Escherichia coli, Enterococcus faecalis and Proteus vulgaris, as well as the concentrations of total phenols and flavonoids in the extracts. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. The concentrations of total phenols were examined by using Folin-Ciocalteu reagent and ranged between 67.55 to 142.46 mg GAE/g. The concentrations of flavonoids in extracts were determined using spectrophotometric method with aluminum chloride and the values ranged from 42.11 to 63.68 mg RUE/g. The aqueous extract of C. vulgaris showed a significant antibacterial activity. The values of MIC were in the range from 2.5 mg/ml to 20 mg/ml for this extract. Proteus vulgaris strains were found to be the most sensitive. The results obtained suggest that all tested extracts of C. vulgaris inhibit the growth of human pathogens, especially the aqueous extract.
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| first_indexed | 2024-04-24T23:32:44Z |
| format | Article |
| id | doaj.art-b16a0b1134444e869ac11d23fa011843 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:32:44Z |
| publishDate | 2014-11-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-b16a0b1134444e869ac11d23fa0118432024-03-15T14:33:07ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2014-11-0114410.17305/bjbms.2014.4.4028In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogensDragana M Vučić0Miroslav R Petković1Branka B Rodić-Grabovac2Olgica D Stefanović3Sava M Vasić4Ljiljana R Čomić5University of Banja LukaUniversity of Banja LukaUniversity of Banja LukaUniversity of KragujevacUniversity of KragujevacUniversity of Kragujevac Calluna vulgaris L. Hull (Ericaceae) has been used for treatment of urinary tract infections in traditional medicine. In this study we analyzed in vitro antibacterial activity of the plant extracts on different strains of Escherichia coli, Enterococcus faecalis and Proteus vulgaris, as well as the concentrations of total phenols and flavonoids in the extracts. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. The concentrations of total phenols were examined by using Folin-Ciocalteu reagent and ranged between 67.55 to 142.46 mg GAE/g. The concentrations of flavonoids in extracts were determined using spectrophotometric method with aluminum chloride and the values ranged from 42.11 to 63.68 mg RUE/g. The aqueous extract of C. vulgaris showed a significant antibacterial activity. The values of MIC were in the range from 2.5 mg/ml to 20 mg/ml for this extract. Proteus vulgaris strains were found to be the most sensitive. The results obtained suggest that all tested extracts of C. vulgaris inhibit the growth of human pathogens, especially the aqueous extract. https://www.bjbms.org/ojs/index.php/bjbms/article/view/40heatherphenolsflavonoidsantibacterial activitydrug activity |
| spellingShingle | Dragana M Vučić Miroslav R Petković Branka B Rodić-Grabovac Olgica D Stefanović Sava M Vasić Ljiljana R Čomić In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens Biomolecules & Biomedicine heather phenols flavonoids antibacterial activity drug activity |
| title | In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens |
| title_full | In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens |
| title_fullStr | In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens |
| title_full_unstemmed | In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens |
| title_short | In vitro activity of heather [Calluna vulgaris (L.) Hull] extracts on selected urinary tract pathogens |
| title_sort | in vitro activity of heather calluna vulgaris l hull extracts on selected urinary tract pathogens |
| topic | heather phenols flavonoids antibacterial activity drug activity |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/40 |
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