Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy
Objective: Low fetal resistance to hypoxia is a factor in stillbirth and neonatal encephalopathy. This review examines fetal movement patterns in response to hypoxia as a predictor of the likelihood of stillbirth. Monitoring the dynamics of fetal movements during maternal apnea could allow the asses...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2024-02-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/51/2/10.31083/j.ceog5102033 |
| _version_ | 1797290984977989632 |
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| author | Petr Shabanov Aleksandr Samorodov Natalya Urakova Evgeny Fisher Albina Shchemeleva |
| author_facet | Petr Shabanov Aleksandr Samorodov Natalya Urakova Evgeny Fisher Albina Shchemeleva |
| author_sort | Petr Shabanov |
| collection | DOAJ |
| description | Objective: Low fetal resistance to hypoxia is a factor in stillbirth and neonatal encephalopathy. This review examines fetal movement patterns in response to hypoxia as a predictor of the likelihood of stillbirth. Monitoring the dynamics of fetal movements during maternal apnea could allow the assessment of fetal resistance to hypoxia. The goal of this study is to describe the practical application of this method by doctors and pregnant women. Mechanism: We searched relevant keywords in the international scientific literature databases Scopus and Web of Science, as well as databases for patents granted in China, India, USA, Japan, Germany, Russia and other countries. Devices, drugs and medical technologies that provide diagnosis, modeling, prevention and treatment of intrauterine fetal hypoxia, stillbirth and neonatal encephalopathy were considered. Findings in Brief: During apnea by a pregnant woman in the second half of normal pregnancy, if the maximum duration of fetal immobility exceeds 30 seconds from the onset of breath-holding, then the fetus is considered to show good resistance to hypoxia, thus preserving its health and life during vaginal delivery. On the other hand, excessive fetal movements <10 seconds after the onset of apnea in a pregnant woman indicates low fetal resistance to hypoxia. When fetal resistance to hypoxia is low, there is no alternative to immediate cesarean section for the preservation of fetal life and health. Conclusions: The monitoring of fetal movements during apnea in pregnant women allows real-time assessment of fetal resistance to intrauterine hypoxia. Obtaining timely information on fetal resistance to hypoxia is critical for determining the optimal timing and type of delivery in order to prevent encephalopathy and stillbirth. |
| first_indexed | 2024-03-07T19:29:14Z |
| format | Article |
| id | doaj.art-b16c454b08874d44900297bba297e42b |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-03-07T19:29:14Z |
| publishDate | 2024-02-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-b16c454b08874d44900297bba297e42b2024-02-29T08:28:10ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632024-02-015123310.31083/j.ceog5102033S0390-6663(23)02280-7Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal EncephalopathyPetr Shabanov0Aleksandr Samorodov1Natalya Urakova2Evgeny Fisher3Albina Shchemeleva4Department of Psychopharmacology, Institute of Experimental Medicine, 197376 Saint Petersburg, RussiaDepartment of Pharmacology with a Course of Сlinical Pharmacology, Bashkir State Medical University, 450008 Ufa, Bashkortostan, RussiaDepartment of Obstetrics and Gynecology, Izhevsk State Medical Academy, 426034 Izhevsk, Udmurt Republic, RussiaDepartment of Experimental and Clinical Research and Inventive, Institute of Thermology, 426054 Izhevsk, Udmurt Republic, RussiaDepartment of Experimental and Clinical Research and Inventive, Institute of Thermology, 426054 Izhevsk, Udmurt Republic, RussiaObjective: Low fetal resistance to hypoxia is a factor in stillbirth and neonatal encephalopathy. This review examines fetal movement patterns in response to hypoxia as a predictor of the likelihood of stillbirth. Monitoring the dynamics of fetal movements during maternal apnea could allow the assessment of fetal resistance to hypoxia. The goal of this study is to describe the practical application of this method by doctors and pregnant women. Mechanism: We searched relevant keywords in the international scientific literature databases Scopus and Web of Science, as well as databases for patents granted in China, India, USA, Japan, Germany, Russia and other countries. Devices, drugs and medical technologies that provide diagnosis, modeling, prevention and treatment of intrauterine fetal hypoxia, stillbirth and neonatal encephalopathy were considered. Findings in Brief: During apnea by a pregnant woman in the second half of normal pregnancy, if the maximum duration of fetal immobility exceeds 30 seconds from the onset of breath-holding, then the fetus is considered to show good resistance to hypoxia, thus preserving its health and life during vaginal delivery. On the other hand, excessive fetal movements <10 seconds after the onset of apnea in a pregnant woman indicates low fetal resistance to hypoxia. When fetal resistance to hypoxia is low, there is no alternative to immediate cesarean section for the preservation of fetal life and health. Conclusions: The monitoring of fetal movements during apnea in pregnant women allows real-time assessment of fetal resistance to intrauterine hypoxia. Obtaining timely information on fetal resistance to hypoxia is critical for determining the optimal timing and type of delivery in order to prevent encephalopathy and stillbirth.https://www.imrpress.com/journal/CEOG/51/2/10.31083/j.ceog5102033fetal movementhypoxiaresistancereservesstillbirth |
| spellingShingle | Petr Shabanov Aleksandr Samorodov Natalya Urakova Evgeny Fisher Albina Shchemeleva Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy Clinical and Experimental Obstetrics & Gynecology fetal movement hypoxia resistance reserves stillbirth |
| title | Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy |
| title_full | Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy |
| title_fullStr | Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy |
| title_full_unstemmed | Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy |
| title_short | Low Fetal Resistance to Hypoxia as a Cause of Stillbirth and Neonatal Encephalopathy |
| title_sort | low fetal resistance to hypoxia as a cause of stillbirth and neonatal encephalopathy |
| topic | fetal movement hypoxia resistance reserves stillbirth |
| url | https://www.imrpress.com/journal/CEOG/51/2/10.31083/j.ceog5102033 |
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