Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study.

Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study.

Cell free deoxyribonucleic acid (cfDNA) has been proposed as a biomarker of secondary complications following trauma. Raised thrombomodulin and syndecan-1 levels have been used to indicate endotheliopathy, and are associated with inflammation, coagulopathy, and mortality. The current study aimed to...

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Bibliographic Details
Main Authors: David N Naumann, Jon Hazeldine, Robert J Dinsdale, Jon R Bishop, Mark J Midwinter, Paul Harrison, Sam D Hutchings, Janet M Lord
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5736230?pdf=render

Internet

http://europepmc.org/articles/PMC5736230?pdf=render

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