Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic
Abstract Background In women of reproductive age, polycystic ovary syndrome (PCOS) constitutes the most frequent endocrine disorder. Women with PCOS are considered to typically belong to an age and sex group which is at lower risk for severe COVID-19. Main body Emerging data link the risk of severe...
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| Format: | Article |
| Language: | English |
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BMC
2020-07-01
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| Series: | BMC Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12916-020-01697-5 |
| _version_ | 1828323738024673280 |
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| author | Ioannis Kyrou Emmanouil Karteris Tim Robbins Kamaljit Chatha Fotios Drenos Harpal S. Randeva |
| author_facet | Ioannis Kyrou Emmanouil Karteris Tim Robbins Kamaljit Chatha Fotios Drenos Harpal S. Randeva |
| author_sort | Ioannis Kyrou |
| collection | DOAJ |
| description | Abstract Background In women of reproductive age, polycystic ovary syndrome (PCOS) constitutes the most frequent endocrine disorder. Women with PCOS are considered to typically belong to an age and sex group which is at lower risk for severe COVID-19. Main body Emerging data link the risk of severe COVID-19 with certain factors such as hyper-inflammation, ethnicity predisposition, low vitamin D levels, and hyperandrogenism, all of which have known direct associations with PCOS. Moreover, in this common female patient population, there is markedly high prevalence of multiple cardio-metabolic conditions, such as type 2 diabetes, obesity, and hypertension, which may significantly increase the risk for adverse COVID-19-related outcomes. This strong overlap of risk factors for both worse PCOS cardio-metabolic manifestations and severe COVID-19 should be highlighted for the clinical practice, particularly since women with PCOS often receive fragmented care from multiple healthcare services. Comprehensively informing women with PCOS regarding the potential risks from COVID-19 and how this may affect their management is also essential. Conclusion Despite the immense challenges posed by the COVID-19 outbreak to the healthcare systems in affected countries, attention should be directed to maintain a high standard of care for complex patients such as many women with PCOS and provide relevant practical recommendations for optimal management in the setting of this fast moving pandemic. |
| first_indexed | 2024-04-13T18:56:38Z |
| format | Article |
| id | doaj.art-b172660322a940f88bceecf0a7e77563 |
| institution | Directory Open Access Journal |
| issn | 1741-7015 |
| language | English |
| last_indexed | 2024-04-13T18:56:38Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medicine |
| spelling | doaj.art-b172660322a940f88bceecf0a7e775632022-12-22T02:34:14ZengBMCBMC Medicine1741-70152020-07-0118111010.1186/s12916-020-01697-5Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemicIoannis Kyrou0Emmanouil Karteris1Tim Robbins2Kamaljit Chatha3Fotios Drenos4Harpal S. Randeva5Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals Coventry and Warwickshire NHS TrustCollege of Health and Life Sciences, Brunel University LondonWarwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals Coventry and Warwickshire NHS TrustDepartment of Biochemistry and Immunology, University Hospitals Coventry and Warwickshire NHS TrustCollege of Health and Life Sciences, Brunel University LondonWarwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals Coventry and Warwickshire NHS TrustAbstract Background In women of reproductive age, polycystic ovary syndrome (PCOS) constitutes the most frequent endocrine disorder. Women with PCOS are considered to typically belong to an age and sex group which is at lower risk for severe COVID-19. Main body Emerging data link the risk of severe COVID-19 with certain factors such as hyper-inflammation, ethnicity predisposition, low vitamin D levels, and hyperandrogenism, all of which have known direct associations with PCOS. Moreover, in this common female patient population, there is markedly high prevalence of multiple cardio-metabolic conditions, such as type 2 diabetes, obesity, and hypertension, which may significantly increase the risk for adverse COVID-19-related outcomes. This strong overlap of risk factors for both worse PCOS cardio-metabolic manifestations and severe COVID-19 should be highlighted for the clinical practice, particularly since women with PCOS often receive fragmented care from multiple healthcare services. Comprehensively informing women with PCOS regarding the potential risks from COVID-19 and how this may affect their management is also essential. Conclusion Despite the immense challenges posed by the COVID-19 outbreak to the healthcare systems in affected countries, attention should be directed to maintain a high standard of care for complex patients such as many women with PCOS and provide relevant practical recommendations for optimal management in the setting of this fast moving pandemic.http://link.springer.com/article/10.1186/s12916-020-01697-5Polycystic ovary syndromePCOSCOVID-19Severe acute respiratory syndrome coronavirus-2SARS-CoV-2Diabetes |
| spellingShingle | Ioannis Kyrou Emmanouil Karteris Tim Robbins Kamaljit Chatha Fotios Drenos Harpal S. Randeva Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic BMC Medicine Polycystic ovary syndrome PCOS COVID-19 Severe acute respiratory syndrome coronavirus-2 SARS-CoV-2 Diabetes |
| title | Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic |
| title_full | Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic |
| title_fullStr | Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic |
| title_full_unstemmed | Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic |
| title_short | Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic |
| title_sort | polycystic ovary syndrome pcos and covid 19 an overlooked female patient population at potentially higher risk during the covid 19 pandemic |
| topic | Polycystic ovary syndrome PCOS COVID-19 Severe acute respiratory syndrome coronavirus-2 SARS-CoV-2 Diabetes |
| url | http://link.springer.com/article/10.1186/s12916-020-01697-5 |
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