Tablet characteristics and pharmacokinetics of orally disintegrating tablets containing coenzyme Q10 granules prepared by different methods

Tablet characteristics and pharmacokinetics of orally disintegrating tablets containing coenzyme Q10 granules prepared by different methods

This study aimed to elucidate the characteristics and pharmacokinetics of orally disintegrating tablets (ODTs) containing coenzyme Q10 (CoQ10) granules prepared by spray drying, hot-melting, and wet granulation. The hardness and disintegration times of CoQ10-ODTs containing 5 % crospovidone were 61....

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Bibliographic Details
Main Authors: Kashiwagura Yasuharu, Takusagawa Shota, Ikematsu Yasuyuki, Tanaka Shimako, Namiki Noriyuki, Uchida Shinya
Format: Article
Language:English
Published: Sciendo 2023-03-01
Series:Acta Pharmaceutica
Subjects:
coenzyme q10
orally disintegrating tablets
granules
spray drying
tablet characteristics
pharmacokinetics
Online Access:https://doi.org/10.2478/acph-2023-0007

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