Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer’s disease

Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer’s disease

Abstract Background New fluid biomarkers for Alzheimer's disease (AD) that reveal synaptic and neural network dysfunctions are needed for clinical practice and therapeutic trial design. Dense core vesicle (DCV) cargos are promising cerebrospinal fluid (CSF) indicators of synaptic failure in AD...

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Bibliographic Details
Main Authors: Neus Barranco, Virginia Plá, Daniel Alcolea, Irene Sánchez-Domínguez, Reiner Fischer-Colbrie, Isidro Ferrer, Alberto Lleó, Fernando Aguado
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Translational Neurodegeneration
Subjects:
Alzheimer’s disease
Biomarkers
Cerebral cortex
Cerebrospinal fluid
Granulovacuolar degeneration
PCSK1
Online Access:https://doi.org/10.1186/s40035-021-00263-0

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