Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/14/4476 |
| _version_ | 1797444871994212352 |
|---|---|
| author | Tong Chen Fan Jia Yue Yu Wufan Zhang Chaoying Wang Shiqin Zhu Nana Zhang Xinmin Liu |
| author_facet | Tong Chen Fan Jia Yue Yu Wufan Zhang Chaoying Wang Shiqin Zhu Nana Zhang Xinmin Liu |
| author_sort | Tong Chen |
| collection | DOAJ |
| description | Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS. |
| first_indexed | 2024-03-09T13:18:45Z |
| format | Article |
| id | doaj.art-b17ab0c4e5d14fbb84c7c4a83a622bb0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T13:18:45Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-b17ab0c4e5d14fbb84c7c4a83a622bb02023-11-30T21:33:34ZengMDPI AGMolecules1420-30492022-07-012714447610.3390/molecules27144476Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A ReviewTong Chen0Fan Jia1Yue Yu2Wufan Zhang3Chaoying Wang4Shiqin Zhu5Nana Zhang6Xinmin Liu7Department of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Gynecology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaPolycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS.https://www.mdpi.com/1420-3049/27/14/4476quercetinantioxidantpolycystic ovary syndromemechanism |
| spellingShingle | Tong Chen Fan Jia Yue Yu Wufan Zhang Chaoying Wang Shiqin Zhu Nana Zhang Xinmin Liu Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review Molecules quercetin antioxidant polycystic ovary syndrome mechanism |
| title | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
| title_full | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
| title_fullStr | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
| title_full_unstemmed | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
| title_short | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
| title_sort | potential role of quercetin in polycystic ovary syndrome and its complications a review |
| topic | quercetin antioxidant polycystic ovary syndrome mechanism |
| url | https://www.mdpi.com/1420-3049/27/14/4476 |
| work_keys_str_mv | AT tongchen potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT fanjia potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT yueyu potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT wufanzhang potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT chaoyingwang potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT shiqinzhu potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT nanazhang potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview AT xinminliu potentialroleofquercetininpolycysticovarysyndromeanditscomplicationsareview |