Comparison of Repeated Doses of C-kit-Positive Cardiac Cells versus a Single Equivalent Combined Dose in a Murine Model of Chronic Ischemic Cardiomyopathy

Comparison of Repeated Doses of C-kit-Positive Cardiac Cells versus a Single Equivalent Combined Dose in a Murine Model of Chronic Ischemic Cardiomyopathy

Using a murine model of chronic ischemic cardiomyopathy caused by an old myocardial infarction (MI), we have previously found that three doses of 1 × 10<sup>6</sup> c-kit positive cardiac cells (CPCs) are more effective than a single dose of 1 × 10<sup>6</sup> cells. The goal...

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Bibliographic Details
Main Authors: Qianhong Li, Yiru Guo, Yibing Nong, Alex Tomlin, Anna Gumpert, Xiaoping Zhu, Syed Adeel Hassan, Roberto Bolli
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
c-kit-positive cardiac cells
multiple doses
cell therapy
chronic ischemic cardiomyopathy
reperfused myocardial infarction
Online Access:https://www.mdpi.com/1422-0067/22/6/3145

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